Introducing a Novel HipH Resin for Bispecific Antibody Purification

Introducing a Novel HipH Resin for Bispecific Antibody Purification

Join Purolite's Field Applications Specialist, Tony Thomas, and Kayla Barry, Senior Engineer from MabPlex, as they present findings on the efficient purification of several bispecific antibodies using Purolite’s novel Protein A resin that allows for elution of antibodies at higher pH. Significant improvements in performance and productivity result in significantly increased monomer purity in comparison with traditional Protein A resins.

Tony will also be taking a deep-dive into Purolite's Jetting technology, a continuous emulsification technology by which all Praesto chromatography resins are produced. This proprietary technology results in resins with a narrow, almost uniform particle size distribution, with excellent mass transfer properties.

Key Learning Objectives:

• Resin comparison study with two bispecifics, Purolite™ Praesto™ Jetted A50 HipH and a standard Protein A resin
• Overview of Jetting Technology.   
• Process intensification, Purolite Praesto Jetted A50
• Introduction to Purolite Jetted A50 HipH.