Bioprocessing (English only)
Accelerate your biologic drug development with Praesto®
We have 40 years of dedicated expertise in resin bead manufacture and 30 years of regulatory experience, delivering innovative resin products to global pharmaceutical, food, beverage, cosmetic and fine chemical industries.
Our field-based Technical Specialists and R&D teams are always on hand to offer guidance on both selecting the best resin and achieving optimal results with your product. We're with you every step of the way, to aid your success in column packing, troubleshooting and overall process economics.
Our dedicated bioprocessing column packing suite is equipped with best-in-class pilot and process-scale equipment commonly used for mAb purification. Here, we provide expert, hands-on training to increase your packing success rates at both pilot and process scales, as well as demonstrate scale-up performance of our Praesto® bioprocessing resins.
Whether you use manual or automated packing methods, we provide guidance on topics such as packing/unpacking, column priming, pressure flow testing, efficiency testing and slurry/buffer preparation. We have detailed packing instructions for our Protein A and Ion Exchange resins below.
If you have any further questions, contact your local Purolite office for additional technical support.
SMART Cycling combines the latest Protein A resin technology with minor changes to your process (i.e. reduced column bed height) to achieve the best mAb purification results possible, depending on your goals.
Whether your pain point is productivity, buffer consumption, process time or cost, our process models provide quick and easy guidelines to achieve your goals with your existing facility fit.
By utilizing SMART cycling, the following process improvements can be achieved:
Praesto Jetting technology offers precise control over agarose bead sizes. This allows our R&D scientists to work hand-in-hand with our customers to development custom particle sized chromatography resins for optimal purification. This service is available upon request.
Anion Exchange Chromatography - Agarose Base
Cation Exchange Chromatography - Agarose Base
Protein A Affinity Chromatography