Overview
Literature
Resources

Principal Applications

  • Affinity chromatography for protein and monoclonal antibody purification

Advantages

  • Manufactured using patented Jetting technology to produce uniform particle size
  • Repligen® NGL-ImpactTM A HipH ligand
  • High dynamic binding capacity (up to 60 g/l for polyclonal hIgG)
  • Specifically designed for eluting Fc-containing molecules at milder pH
  • Alkaline stable protein A resin
  • 環境への負荷を低減して製造

Regulatory Approvals

  • Full regulatory support available

Typical Packaging

  • バルク樹脂
  • 生産スケール OPUS® Columns
  • OPUS® Robocolumns®
  • OPUS® MiniChrom Columns
  • HT カラム

Typical Physical & Chemical Characteristics:

ポリマー構造 Highly cross linked agarose
官能基 Protein A
平均粒径 (d50ᵥ), μm 50 µm
粒径範囲 (um) 95% between 35-90 µm
Dynamic binding capacity Up to ~60 mg hIgG/ml resin
Pressure/flow specifications Up to 200 cm/h (30 x 20 cm column)
pH安定性, CIP (短期) 2 - 13
pH安定性, 運転時 3 - 12
推奨保管条件 2 - 8°C in 20% ethanol / 2% benzyl alcohol. Shipped in 20% ethanol / 2 % benzyl alcohol on request.