Overview
Literature

Principal Applications

  • Affinity chromatography for protein and monoclonal antibody purification

Advantages

  • Manufactured using patented Jetting technology to produce uniform particle size
  • Repligen® NGL-ImpactTM A ligand
  • High dynamic binding capacity (up to 80 g/l for polyclonal hIgG)
  • Alkaline stable protein A resin
  • 環境への負荷を低減して製造

Regulatory Approvals

  • Full regulatory support available

Typical Packaging

  • バルク樹脂
  • 生産スケール OPUS® Columns
  • OPUS® Robocolumns®
  • OPUS® MiniChrom Columns
  • HT カラム

Typical Physical & Chemical Characteristics:

ポリマー構造 Highly cross linked agarose
外観 Spherical, uniform size beads supplied in 20% ethanol slurry. On request 2% benzylalcohol
官能基 Protein A
Dynamic binding capacity Up to 70 mg mAb/ml resin
Up to 80 mg hIgG/ml resin
(10 minute residence time)
平均粒径 50 µm
粒径範囲 (um) >95% between 35-90 µm
Pressure/Flow specifications Up to 200 cm/h (30 x 20 cm)
pH安定性, 運転時 3 - 12
pH安定性, CIP (短期) 2 - 13
推奨保管条件 2 - 8 °C in 20% ethanol / 2% benzyl alcohol. Shipped in 20% ethanol / 2 % benzyl alcohol on request.