Overview
Literature
Resources

Principales aplicaciones

  • Purificación de MAb
  • Purificación de proteínas

Ventajas

  • Manufactured using patented Jetting technique
  • Uniform particle size
  • Enhanced productivity
  • High dynamic binding capacity
  • Enhanced pressure/flow performance
  • Manufactured with reduced environmental impact
  • Secure, validated supply and regulatory support

Aprobaciones reguladoras

  • Manufactured under GMP conditions

Envase típico

  • Bulk Resin
  • Production-Scale OPUS® Columns
  • OPUS® Robocolumns®
  • OPUS® MiniChrom Columns
  • HT Columns

Características físicas y químicas:

Matrix Cross-linked agarose
Grupo funcional CH2CH2CH2S03
Ionic Capacity, mmol/mL Resin 0.11-0.16
Average Particle Size (d50ᵥ), μm 35
Flow Velocity cm/h at 3 bar in a 2.6 x 20 cm Column (packed at 4 bar) > 150
Binding Capacity mg/mL Resin at 6’ Residence Time > 90 mg/ml lgG
Operating pH Stability (Short Term) pH 3-14
Operating pH Stability (Long-Term) pH 4-13
Working Temperature 4-30°C
Estabilidad química All commonly used aqueous buffers, 1M NaOH, 8M urea, 6M guanidine hydrochloride, 30% isopropanol and 70% ethanol
Evitar Oxidizing agents, cationic detergents
Storage 20% ethanol, 0.2M sodium acetate, 4-30°C