Overview
Literature

Principales aplicaciones

  • Purificación de MAb
  • Purificación de proteínas

Ventajas

  • Manufactured using patented Jetting technique
  • Uniform particle size
  • Enhanced productivity
  • High dynamic binding capacity
  • Enhanced pressure/flow performance
  • Manufactured with reduced environmental impact
  • Secure, validated supply and regulatory support

Aprobaciones reguladoras

  • Manufactured under GMP conditions

Envase típico

  • Bulk Resin
  • Production-Scale OPUS® Columns
  • OPUS® Robocolumns®
  • OPUS® MiniChrom Columns
  • HT Columns

Características físicas y químicas:

Matrix Cross-linked agarose
Grupo funcional CH2CH2CH2SO3-
Capacidad iónica - medina 0.11 - 0.18 mmol/ml H⁺
Average particle size (d50ᵥ), μm 35 µm
Flow velocity Up to 120 cm/h (30 x 20 cm)
Binding Capacity mg/mL Resin at 6’ Residence Time > 90 mg/ml lgG
Operating pH Stability (Short Term) 3 - 14
Operating pH Stability (Long-Term) 4 - 12
Working Temperature 4 - 30 °C
Estabilidad química All commonly used aqueous buffers, 1M NaOH, 8M urea, 6M guanidine hydrochloride, 30% isopropanol and 70% ethanol
Evitar Oxidizing agents, cationic detergents
Storage 20% ethanol, 0.2M sodium acetate, 4 - 30 °C