Overview

Diagnostics

Clinical diagnostics covers a wide range of applications, such as removal and analysis of:

Antibiotics
APIs
Recreational drugs
Metabolites from human fluids

This is usually achieved using a cartridge containing hydrophobic adsorbent resins, which target hydrophobic components in the blood such as those in the above list.

Adsorbent resins are ideal for capturing and extracting hydrophobic molecules due to their highly hydrophobic nature. To ensure reproducible quantification of target compounds, the resins must be cleaned to a high degree to avoid causing interference during measurements. This makes control of leachables a key feature when selecting a suitable adsorbent for diagnostics.

Purolite provides a range of adsorbents suitable for diagnostic applications, in full compliance with Resap (2004)3 and FDA regulations, and manufactured in ISO-accredited facilities.

An example of resin-based immunotherapy treatments for leukapheresis

Leukapheresis immunotherapy involves the selective removal of specific cells from blood by using adsorbents coupled with specific ligands. These resins are suitable for treatment of diseases such as:

Cancer
Diabetes
Obesity
Allergies
Atherosclerosis

Another emerging application of Leukapheresis Immunotherapy is the treatment of patients who are due to have organ transplants. Patients need to have immunoglobulins removed as these antibodies can lead to transplanted organs being rejected. This new treatment uses affinity ligands and is administered a few days prior to the operation. This procedure can improve life expectancy by as much as 30% in some cases.

Diagnostics Productos por Aplicación

Adsorbentes

PAD1200

Polydivinylbenzene Macroporoso Adsorbente Non-Ionic Form, 240 Å pores

PAD400

Polydivinylbenzene Macroporoso Adsorbente Non-Ionic Form, 360 Å pores

PAD500

Polydivinylbenzene Macroporoso Adsorbente Non-Ionic Form, 110 Å pores, Special Particle Size

PAD600

Polydivinylbenzene Macroporoso Adsorbente Non-Ionic Form, 90 Å pores

PAD610

Polymethacrylic/DVB Macroporoso Adsorbente Non-Ionic Form, 300 Å pores

PAD900

Polydivinylbenzene Macroporoso Adsorbente Non-Ionic Form, 220 Å pores

PAD950

Polymethacrylic Macroporoso Adsorbente Non-Ionic Form, 120 Å pores

PAD950C

Polymethacrylic Macroporoso Adsorbente Non-Ionic Form, 120 Å pores, Course Particle Size

Ligand Coupling

CNBr

Alto crosslink Pre-Activated Agarose Base Matrix

Epoxy

Alto crosslink Pre-Activated Agarose Base Matrix

MEP/C

Metacrilato de epoxy Macroporoso Affinity Resin, 100 - 300 µm

MEP/F

Metacrilato de epoxy Macroporoso Affinity Resin, 40 - 90 µm

MEP/M

Metacrilato de epoxy Macroporoso Affinity Resin, 75 - 125 µm

NHS

Alto crosslink Pre-Activated Agarose Base Matrix

Lipasas inmovilizadas

CalB immo 8285

Lipase from Candida Antarctica B, covalently immobilized on ECR8285

CalB immo 8806

Lipase from Candida Antarctica B, immobilized by adsorption on ECR8806M

CalB immo Plus

Metacrilato DVB Adsorbente, con lipasa inmovilizada por adsorción

Reversed Phase Chromatography

PCG1200C

Poliestireno Macroporosa adsorbente Non-functionalized Resin, 100 - 200 µm, 300 - 500Å pores

PCG1200F

Poliestireno Macroporosa adsorbente Non-functionalized Resin, 20 - 50 µm, 300 - 500Å pores

PCG1200M

Poliestireno Macroporosa adsorbente Non-functionalized Resin, 50 - 100 µm, 300 - 500Å pores

PCG1200MHEMA

Polymethacrylic/DVB Macroporosa adsorbente Non-functionalized Resin, 50 - 100 µm, 200 - 400Å pores

PCG600C

Poliestireno Macroporosa adsorbente Non-functionalized Resin, 100 - 200 µm, 75 - 150Å pores

PCG600F

Poliestireno Macroporosa adsorbente Non-functionalized Resin, 20 - 50 µm, 75 - 150Å pores

PCG600M

Poliestireno Macroporosa adsorbente Non-functionalized Resin, 50 - 100 µm, 75 - 150Å pores

PCG900C

Poliestireno Macroporosa adsorbente Non-functionalized Resin, 100 - 200 µm, 150 - 300Å pores

PCG900F

Poliestireno Macroporosa adsorbente Non-functionalized Resin, 20 - 50 µm, 150 - 300Å pores

PCG900M

Poliestireno Macroporosa adsorbente Non-functionalized Resin, 50 - 100 µm, 150 - 300Å pores

PCG950C

Polymethacrylic Macroporosa adsorbente Non-functionalized Resin, 100 - 200 µm

PCG950F

Polymethacrylic Macroporosa adsorbente Non-functionalized Resin, 20 - 50 µm

PCG950M

Polymethacrylic Macroporosa adsorbente Non-functionalized Resin, 100 - 200 µm

Tecnologías centrales

Tipo de producto

Adsorbents

Resina mixta

Resina Catiónica Debilmente ácida

Resina Aniónica Debilmente Básica

Industria

Productos químicos finos

Alimentos y bebidas

Zumo de frutas

Azúcar

Edulcorante

Potable y agua subterránea

Energía

Nuclear

Aplicación

Ciencias de la salud y la vida

Biopharmaceuticals and Antibody Processing

Pharmaceutical

Medical Devices & Diagnostics

Nutraceuticals

Analytical Lab Testing and Screening

Empresa

Aplicación

Acerca de Nosotros

Leadership

Brands

Industria

Certifications

Empresa

Tipo de producto

Clinical Diagnostics

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Overview

Diagnostics

Diagnostics Productos por Aplicación