Overview
Literature

Principali applicazioni

  • Protein purification (up to 250 kDa)
  • Purificazione dei Mabs

Vantaggi

  • High productivity
  • Alkaline stable
  • Ultra-high dynamic binding capacity
  • Enhanced pressure/flow performance
  • Low protein A leaching
  • Secure, validated supply and regulatory support

Certificazioni

  • Manufactured under GMP conditions

Imballi tipici

  • Bulk Resin
  • Production-Scale OPUS® Columns
  • OPUS® MiniChrom Columns
  • OPUS® Robocolumns®
  • HT Columns

Caratteristiche chimiche e fisiche tipiche:

Struttura del polimero Highly cross linked agarose
Ligand Alkali stabilized recombinant Protein A
Dynamic binding capacity Up to 60 mg mAb/ml resin (6 minute residence time)
Jetted Particle Size 80 µm
Distribuzione granulometrica - µm ≥ 95% within range 45 - 125 cm/h
Pressure/Flow specifications Up to 400 cm/h (30 x 25 cm)
pH di stabilità, range operativo 3 - 12
Stabilità del pH, CIP (a breve termine) 2 - 13
Conservazione/Stoccaggio consigliato 2 - 8 °C in 20% ethanol