Accelerate your biologic drug development with Praesto®
I nostri team di assistenza e supporto tecnico sempre pronti fanno il passo in più per essere la tua risorsa più affidabile. Siamo qui per voi.
Peracetic acid, a derivative of hydrogen peroxide, is a good treatment against a wide variety of microbes. Research has shown that peracetic acid will be used to an ever-increasing degree in the field of medicine due to its anti-bacterial, fungicidal, sporicidal and anti-viral action.
Work done by the Degussa Technical Applications Department in conjunction with Chemiewerk Homburg AG determined that peracetic acid is suitable as a disinfectant for deionizers because of its wide spectrum of attack. Using a 0.1% peracetic acid solution in water with a reaction time of one hour, a slime and mold concentration of 104–105/mL was reduced to almost zero. The short rinsing time after using peracetic acid is of importance (typically about 45 minutes or 10–15 BV).
If peracetic acid is used as a disinfectant, the following procedure should be used for both cation and anion resin.
Ensure anion resins are fully exhausted as peracetic acid performs best at a pH < 8.
Make up 1 bed volume (BV) of peracetic acid solution containing 0.1% peracetic acid.
Inject 1 BV of disinfectant at a flow rate of 5 BV/h (0.6 USGM/ft3) with displacement discharged to a drain approved for chemical waste disposal.
When all the peracetic acid has been injected, close all valves and retain the disinfectant for at least one hour to soak the resin and pipe work.
Carry out a displacement rinse using raw water for at least 60 minutes at 5 BV/h, followed by a fast flush for 30 minutes.
Regenerate the resin once and return the unit to service.