Affinity Chromatography Resins for Complex Antibody Purification

Antibody Innovation in Therapeutics

Monoclonal antibodies have reshaped modern medicine, and now a new wave of complex formats, like bispecifics and fragments, is driving the next revolution. These molecules offer exciting potential but also bring unique purification challenges. Their diverse structures often render standard monoclonal approaches ineffective, risking bioactive loss through aggregation and limiting the use of Fc binding for efficient purification.
 

Addressing Antibody Purification 

Ecolab produce a range of affinity resins for monoclonal antibody purification, with two showing specific properties that make them particularly successful in complex molecule purification: Praesto™ 70 CH1 and Praesto™ Jetted A50 HipH.