Overview
Literature
Resources

Applications principales

  • MAb Purification
  • Protein purification (20-500 kDa)

Avantages

  • Manufactured using patented Jetting technique
  • Granulométrie uniforme
  • Enhanced productivity
  • High dynamic binding capacity
  • Enhanced pressure/flow performance
  • Manufactured with reduced environmental impact
  • Secure, validated supply and regulatory support

Autorisations réglementaires

  • Manufactured under GMP conditions

Conditionnement classique

  • Bulk Resin
  • Production-Scale OPUS® Columns
  • OPUS® Robocolumns®
  • OPUS® MiniChrom Columns
  • HT Columns

Caractéristiques physico-chimiques typiques

Matrix Cross-linked agarose
Groupe fonctionnel CH2CH2CH2S03
Ionic Capacity, mmol/mL Resin 0.11-0.16
Average Particle Size (d50ᵥ), μm 35
Flow Velocity cm/h at 3 bar in a 2.6 x 20 cm Column (packed at 4 bar) > 150
Binding Capacity mg/mL Resin at 6’ Residence Time > 90 mg/ml lgG
Operating pH Stability (Short Term) pH 3-14
Operating pH Stability (Long-Term) pH 4-13
Working Temperature 4-30°C
Chemical stability All commonly used aqueous buffers, 1M NaOH, 8M urea, 6M guanidine hydrochloride, 30% isopropanol and 70% ethanol
Avoid Oxidizing agents, cationic detergents
Storage 20% ethanol, 0.2M sodium acetate, 4-30°C