Overview
Literature
Resources

Applications principales

  • Protein purification (20-500 kDa)
  • MAb Purification

Avantages

  • Manufactured using patented Jetting technique
  • Granulométrie uniforme
  • Repligen® NGL-ImpactTM A ligand
  • Highest dynamic binding capacity (~80g/l)
  • Exceptional alkaline stability
  • Enhanced pressure/flow performance
  • Manufactured with reduced environmental impact

Autorisations réglementaires

  • Manufactured under GMP conditions

Conditionnement classique

  • Bulk Resin
  • Production-Scale OPUS® Columns
  • OPUS® Robocolumns®
  • OPUS® MiniChrom Columns
  • HT Columns

Caractéristiques physico-chimiques typiques

Structure polymérique Highly cross linked agarose
Apparence Spherical, uniform size beads supplied in 20% ethanol slurry. On request 2% benzylalcohol
Groupe fonctionnel Protein A
Average Particle Size (d50ᵥ), μm 50 µm
Particle size range (micron) 95% between 35-90 µm (Uniformity coefficient = <1.3)
Dynamic Binding Capacity (min.)- 3 minutes residence time ~ 50 g/l at 3 mins residence time and up to ~80 g/l at 10 mins residence time
Pressure/flow (min.) - at 3 bar in a 2.6 x 20 cm column (pressure-packed at 4 bar) > 300 cm/h
pH stability, CIP (short term) 2 - 14
pH stability, working range 3 - 12
Recommended Storage 2 - 8 °C
Recommended Storage 20% ethanol