Praesto Jetted A50 is an agarose-based novel Protein A affinity resin with industry-leading performance characteristics, and utilizes a new ligand from Repligen Corporation - NGL-ImpactTM A. Praesto Jetted A50 beads are manufactured using patented 'Jetting' technology, an innovative process that produces uniform size agarose beads with a very narrow particle size distribution.

These uniform particle sizes deliver superior performance characteristics over traditional resins. 

Our mAb purification specialists are always available to help you solve your process challenges. Contact us for fast reliable support or visit our FAQs page. 

Principal Applications

  • Protein purification (20-500 kDa)
  • MAb Purification

Advantages

  • Uniform particle size
  • Repligen® NGL-ImpactTM A ligand
  • Highest dynamic binding capacity (~80g/l)
  • Exceptional alkaline stability
  • Enhanced pressure/flow performance
  • Manufactured with reduced environmental impact

Regulatory Approvals

  • Manufactured under cGMP conditions

Typical Packaging

  • Bulk Resin
  • Production-Scale OPUS® Columns
  • OPUS® Robocolumns®
  • OPUS® MiniChrom Columns
  • HT Columns

Typical Physical & Chemical Characteristics:

Polymer Structure Highly cross linked agarose
Appearance Spherical, uniform size beads supplied in 20% ethanol slurry. On request 2% benzylalcohol
Functional Group Protein A
Average Particle Size (d50ᵥ), μm 50 µm
Particle size range (micron) 95% between 35-90 µm (Uniformity coefficient = <1.3)
Dynamic Binding Capacity (min.)- 3 minutes residence time ~ 50 g/l at 3 mins residence time and up to ~80 g/l at 10 mins residence time
Pressure/flow (min.) - at 3 bar in a 2.6 x 20 cm column (pressure-packed at 4 bar) > 300 cm/h
pH stability, CIP (short term) 2 - 14
pH stability, working range 3 - 12
Recommended Storage 2 - 8 °C
Recommended Storage 20% ethanol