Overview
Literature

Principal Applications

  • Affinity chromatography for protein and monoclonal antibody purification

Advantages

  • Manufactured using patented Jetting technology to produce uniform particle size
  • Repligen® NGL-ImpactTM A ligand
  • High dynamic binding capacity (up to 80 g/l for polyclonal hIgG)
  • Alkaline stable protein A resin
  • Manufactured with reduced environmental impact

Regulatory Approvals

  • Full regulatory support available

Typical Packaging

  • Bulk Resin
  • Production-Scale OPUS® Columns
  • OPUS® Robocolumns®
  • OPUS® MiniChrom Columns
  • HT Columns

Typical Physical & Chemical Characteristics:

Polymer structure Highly cross linked agarose
Appearance Spherical, uniform size beads supplied in 20% ethanol slurry. On request 2% benzylalcohol
Functional group Protein A
Dynamic binding capacity Up to 70 mg mAb/ml resin
Up to 80 mg hIgG/ml resin
(10 minute residence time)
Average Particle Size 50 µm
Particle size range (micron) >95% between 35-90 µm
Pressure/Flow specifications Up to 200 cm/h (30 x 20 cm)
pH stability, working range 3 - 12
pH stability, CIP (short term) 2 - 13
Recommended storage 2 - 8 °C in 20% ethanol / 2% benzyl alcohol. Shipped in 20% ethanol / 2 % benzyl alcohol on request.