Bioprocessing

Accelerate your biologic drug development with Praesto® 
chromatography resins.

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Monoclonal antibody and recombinant protein purification
Monoclonal antibody and recombinant protein purification
Products
Products
Praesto® Jetted A50 HipH Praesto® Jetted A50
Jetting Technology Technical Support
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Tools & Services
Field Application Services Throughput & Productivity Calculator

Core Technologies

As a global leader in resin technology, we develop and manufacture small beads that are used in the most regulated industries in the world to separate, remove or recover very specific elements and compounds.

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Product Types
Adsorbents
Adsorbents
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Weak Base Anion Resin
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Industries
Industries
Chemical Processing and Petrochemical Food and Beverage
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Applications
Adsorption Catalysis Condensate Polishing Demineralization Metal Removal and Recovery Organics Removal Softening

Healthcare and Life Sciences

With 40 years of manufacturing expertise and 30 years of regulatory experience, we supply leading separation, purification and extraction technologies to support chromatography and biocatalysis applications in healthcare and life sciences. 

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Pharmaceutical
Pharmaceutical
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Medical Devices and Diagnostics
Overview Biofluid Treatment Diagnostics
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Nutraceuticals
Overview Dairy Protein Isolation Supplement Ingredients Vitamin Purification

Purolite

We are a world leader in resin-based separation, purification and extraction technology, that provides sustainable solutions for our environment, businesses and healthcare.

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About
About
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CriticalResin™ Macronet™ Microlite® Purofine® Puromet™ Puromill™ Puropack® PuroSorb™ Shallow Shell™ UltraClean™
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Principal Applications

  • Affinity chromatography for protein and monoclonal antibody purification

Advantages

  • Manufactured using patented Jetting technology to produce uniform particle size
  • Repligen® NGL-ImpactTM A ligand
  • High dynamic binding capacity (up to 80 g/l for polyclonal hIgG)
  • Alkaline stable protein A resin
  • Manufactured with reduced environmental impact

Regulatory Approvals

  • Full regulatory support available

Typical Packaging

  • Bulk Resin
  • Production-Scale OPUS® Columns
  • OPUS® Robocolumns®
  • OPUS® MiniChrom Columns
  • HT Columns
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DATASHEET

Praesto Jetted A50

Typical Physical & Chemical Characteristics:

Polymer structure Highly cross linked agarose
Appearance Spherical, uniform size beads supplied in 20% ethanol slurry. On request 2% benzylalcohol
Functional group Protein A
Dynamic binding capacity Up to 70 mg mAb/ml resin
Up to 80 mg hIgG/ml resin
(10 minute residence time)
Average Particle Size 50 µm
Particle size range (micron) >95% between 35-90 µm
Pressure/Flow specifications Up to 200 cm/h (30 x 20 cm)
pH stability, working range 3 - 12
pH stability, CIP (short term) 2 - 13
Recommended storage 2- 8 °C in 20% ethanol, 2% benzyl alcohol. Shipped in 20% ethanol, 2 % benzyl alcohol on request.