Bioprocessing Knowledge Hub

Literature

Ecolab, Purolite Affinity Resin Selection Guide

eBook

Explore the full spectrum of Purolite™ Affinity Resins in this comprehensive guide, designed to help you select the ideal solution for any purification challenge.

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Literature

Ion Exchange Chromatography Explained: Techniques & Uses

Educational Guide

Access this concise resource that explains the principles and practical steps for protein purification, with expert tips on resin selection and process optimization.

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Literature

Scaling Protein Purification eBook

Educational Guide

This eBook is designed to guide pharmaceutical developers in scaling their chromatography processes to achieve consistent product quality and faster time to market.

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Webinar

Design of Experiments for Biopharmaceutical Process Development

Chromatography Masterclass

Curious about improving biopharma processes through smarter experimentation? This masterclass workshop introduces Design of Experiments (DoE), a systematic approach to optimize critical process parameters (CPPs). DoE helps you understand how variables interact to influence product purity, yield, and activity.

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Webinar

Maximizing Bioprocess Efficiency: Introducing Ecolab, Purolite Resins Praesto™ AP+50 Affinity Resins

Presentation

Field Applications Scientist Alain Medina presents Ecolab’s latest Praesto affinity resin, at CPHI Frankfurt, designed for protein and monoclonal antibody purification.

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Webinar

Overcoming Downstream Challenges in Next Generation Antibody Development

Presentation

Presented by Grant Gechtman (Bionova Scientific) and Mark Hicks (Ecolab Life Sciences), discover Bionova’s approach to complex modalities and learn from detailed case studies on Purolite™ Praesto™ Jetted HipH and Purolite™ Praesto™ CH1 affinity resins, including rapid implementation and productivity improvements.

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Webinar

Unlocking Bioprocessing Efficiency with Purolite™ Praesto™ AP+50

Presentation

Join Aaron Moulin at BIO in Boston as he unveils Ecolab's latest innovation in Protein A chromatography - Praesto™ AP+50. Designed for intensified downstream processes, this advanced resin delivers exceptional dynamic binding capacity, reduced buffer consumption, and up to 84% resin cost savings.

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Interview

Tackling the Complexities of Multispecific Antibodies

Join Ecolab and Bionova in this deep-dive conversation on the unique challenges and opportunities presented by multispecific antibodies. From early-stage development assessments to advanced purification strategies, this video explores how innovators can streamline bioprocessing and accelerate timelines.

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White Paper

Beyond Traditional Monoclonal Antibodies: Purification Strategies for Novel Biologics

Whitepaper

Explore how Purolite™ resins are enabling the purification of next-generation antibody formats - including bispecifics, Fab fragments, and nanobodies. This whitepaper reveals how innovative affinity technologies like Praesto™ 70 CH1 and Jetted A50 HipH help overcome complex impurity profiles, reduce aggregation, and support scalable biologics production. A must-read for scientists and engineers advancing therapeutic innovation.

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Webinar

Accelerating the Future of Medicine: Redefining Bioprocessing

Presentation

Hear from Hayley Crowe, as she spotlights the transformative innovations reshaping bioprocessing and redefining the pace of therapeutic development. Designed for senior leaders and visionaries in the biopharmaceutical space, this video explores how next-generation resin technologies are driving efficiency, scalability, and regulatory confidence across global operations.

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Case Study

HT Platform Protein Purification Applicability of Praesto Jetted A50 HipH

Case Study

Discover how a global pharma team transformed their high-throughput protein purification platform using Praesto™ Jetted A50 HipH. This case study reveals how switching to a single-step purification process delivered up to 130% more product yield, 50% buffer savings, and 100% productivity gains - without compromising purity.

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White Paper

Evaluation of Protein A Resins for Automated Workflow Utilizing Dispersive Solid-Phase Extraction

Whitepaper

This whitepaper explores the use of dispersive solid-phase extraction in tip-based systems, offering insights into dynamic binding capacity, kinetic performance, and elution efficiency. Whether you're optimizing for high or low titre samples, this study provides the data you need to make informed decisions in biotherapeutic purification workflows.

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White Paper

Innovation and Evolution of Affinity Resins for Monoclonal Antibody Purification

Whitepaper

Affinity chromatography has revolutionized the way monoclonal antibodies (mAbs) are purified -becoming the gold standard for capture steps in biomanufacturing. But how did we get here? And what’s next?

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Literature

Optimizing Downstream Chromatography: Reducing Costs and Maximize Efficiency

eBook

Produced in partnership with GEN - Unlock the full potential of your bioprocessing workflows with Purolite™ Resins engineered for high dynamic binding capacity, faster mass transfer, and superior host cell protein (HCP) clearance.

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Literature

Optimizing Chromatographic Performance: The Role of Packed Bed Height

Whitepaper

Learn how optimizing packed bed height can enhance chromatographic performance, efficiency, and product quality. Download the white paper to learn more about optimizing chromatographic performance.

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Webinar

HiScale Column Packing Video Tutorial

Column Packing Instructions

Join the Ecolab, Purolite Resins team as they provide a step-by-step guide for packing a HiScale chromatography column

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Webinar

Axichrom Column Packing Video Tutorial

Column Packing Instructions

Join the Ecolab, Purolite Resins team as they provide a step-by-step guide for packing a Axichrom chromatography column

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Webinar

Purification of Complex Molecules: Market Growth, Challenges, and Solutions

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Literature

Ecolab, Purolite Ion Exchange Resin Selection Guide

eBook

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Webinar

Navigating Downstream Bioprocessing for Biosimilar Development

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Interview

DurA™ Diaries

Interview with Senior Director Global Product Management, Renato Azevedo

Discussing the latest advancements in pharmaceutical manufacturing aimed at reducing bioburden through more intense cleaning regimes.

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Interview

Ecolab Purolite Resins Commitment to Supporting Drug Development and Innovation

Interview with Craig Cox

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Interview

Innovative Solutions in Bioprocessing Sustainability: Insights from Ecolab

Interview with Global Senior Marketing Manager, Lucia Robles

Lucia highlights our innovative ion exchange and affinity resin toolboxes designed to deliver solutions across APIs, excipients, and antibody purification.

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Webinar

Addressing The Challenges Of Complex Biologic Purification : New Advances In Protein A Resins

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White Paper

Viral clearance under mild pH using protein A resins

Application Note

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White Paper

Impact of Tip-based Systems and Jetting Technology on High Throughput Process Development

Application Note

 

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Interview

Addressing Challenges in Pharma with Innovative Solutions

Interview with Senior Director Global Product Management, Renato Azevedo

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Interview

Leveraging Technology to Advance Protein A Chromatography

Interview with EVP and General Manger of Global Life Sciences, Hayley Crowe

Hayley joins Chris Spivey from Biopharm International to discuss the transformative impact of jetting technology on Protein A resin manufacturing.

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Literature

Powering Sustainability in Pharma eBook

Our latest eBook, ''Powering Sustainability in Pharma'' provides a comprehensive exploration of how innovative practices and solutions can transform your operations while protecting vital resources.

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White Paper

Addressing Host Cell Protein Challenges in Monoclonal Antibody Production

Application Note

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Webinar

Process Scale Column Packing Video Instructions

Column Packing Instructions

Join the Ecolab, Purolite Resins team as they demonstrate the step-by-step guide for packing a Bioprocess Glass (BPG) chromatography column

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Webinar

Column Packing Expertise

Chromatography Masterclass

In this webinar, Field Applications Scientist, Jon Baker and Will Bowen, will cover crucial topics such as resin selection, packing density, bed height uniformity, and troubleshooting common challenges

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White Paper

pH Elution Properties of Purolite™ Affinity Resins

Application Note

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White Paper

Mild pH Elution Benefits of Purolite™ Praesto™ Jetted A50 HipH

Application Note

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Interview

Leveraging Technology to Advance Protein A

Interview with Srini Paluri

Srini shares his excitement about the recent launch of our innovative DurA™ Cycle product.

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White Paper

Contrasting Dynamic Binding Capacity Across Affinity Resins

Application Note

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Literature

Next-Generation Solutions for Affinity Chromatography

Article

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Interview

DurA™ Cycle A50

Interview with Field Applications Scientist, Aaron Moulin

Hear from Aaron Moulin as he discusses Ecolab's latest resin launch, DurA Cycle A50

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Interview

Lower Your Cost of Goods in Bioprocessing Commercial Processes

Interview with David Cartmell

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Interview

Purolite launch DurA™ Cycle Live at BIO 2024

Interview with experts David Cartmell & Renato Azevedo

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Interview

What is Purolite™ DurA™ Cycle A50?

Interview with Field Applications Scientist Aaron Moulin

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Interview

What are the three key trends shaping the CDMO industry?

Interview with Senior Director, Global Marketing and Strategy, Stacey Treichler

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Case Study

Alvotech: Partnership in Innovation

Delivering reliability and innovation through Protein A resin supply at Alvotech.

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Interview

Sustainability Goals Impacting Biopharma

Biopharm International® interview with Stacey Treichler Senior Director of Marketing and Strategy

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Webinar

A Partnership in Innovation: Next-Generation Solutions for Affinity Chromatography

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Interview

Jetted Resin Revolution: Purolite's Biopharma Breakthrough

Interview with Hayley Crowe

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Webinar

Chromatography Masterclass

Unleash the power of chromatography resins in our exclusive course - your gateway to precision and efficiency in developing a purification.

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Literature

The Impact of Elution pH on Product Quality of Fc-Containing Proteins

Scientific Poster

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Literature

Purolite™ DurA™ Cycle A50 Product Brochure

Product Brochure

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Interview

Meet the Team: Field Applications Scientist

No matter the location, our expert field application team members are positioned to help you solve your technical and downstream purification challenges,

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Interview

Women in Science: How Curiosity and Determination Inspired Hayley Crowe's Journey from Bench to C-Suite

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Webinar

Process Intensification Strategies to Improve Protein A Resin Cost Effectiveness

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Literature

Purolite™ DurA™ Cycle A50 Data File

Data File

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Interview

BIO 24: An Interview with Felix Solamo

The European Pharmaceutical Manufacturer caught up with Purolite's Felix Solamo to look back on Bio International 2024 and what it meant for the Company. 

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Literature

Purolite™ DurA™ Cycle A50 Process Scale Column Packing Instructions

Column Packing Instructions

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Interview

Exploring the Role of Agarose Resin in Biomolecule Purification

IMCS Podcast with Andy Masters

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White Paper

Resin Sourcing

Discussing the regulatory pathways for introducing process improvements and/or alternate sources of chromatography resins.

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Webinar

The Advances in Protein A Chromatography

Watch On Demand

Literature

Purolite™ DurA™ Cycle A50 Lab Scale Column Packing Instructions

Column Packing Instructions

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Webinar

Introducing a Novel HipH Resin for Bispecific Antibody Purification

Watch On Demand

Literature

Addressing the Need for High Capacity, Improved Stability, and Innovative Characteristics

Scientific Poster

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White Paper

BioPhorum

Approach to the Registration of Innovative Raw Materials using Quality by Design Principles – Appendix 2: Protein A resins

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Literature

Purolite™ Praesto™ 70 CH1 Data File

Data File

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White Paper

Journal of Chromatography A

Evaluation of mild pH elution protein A resins for antibodies and Fc-fusion proteins

Read the latest journal from Science Direct and find out how Jetted A50 HipH is an ideal candidate for a platform protein A resin.

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Literature

Purolite™ Praesto™ 70 CH1 IFU

Instructions For Use

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Case Study

Adventures in FAB Protein Purification

A faster single-step platform for expressing antibody fragments is helping to speed up development of antibody therapeutics

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Interview

Chromatography Masterclass Q&A

Interview with Penny Hamlyn

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Interview

The Advances in Protein A Chromatography Q&A

Interview with Aaron Moulin

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Literature

Purolite™ Praesto™ 70 CH1 Laboratory Scale Column Packing Instructions

Column Packing Instructions

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Literature

Purolite™ Praesto™ 70 CH1 Pilot Scale Column Packing Instructions

Column Packing Instructions

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Literature

Purolite™ Praesto™ Jetted A50 HipH

Scientific Poster

Maintaining high yields can be a challenge when working with standard protein A resins, which typically elute best at pH 3 – 3.5. Purolite Praesto Jetted A50 HipH has been designed specifically for the elution of Fc-containing molecules up to pH 5.

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Interview

Principles and Benefits of Process Intensification for Affinity Chromatography Q&A

Interview with Field Applications Scientist, William Bowen

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Literature

Purolite™ Praesto™ Jetted A50 HipH Resin Applications for Bispecific Antibody Purification

Scientific Poster

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Interview

Life Science Knowledge Hub Interview Lucia Robles

Lucia about her role within the Pharma Solutions team and how the team supports vital drug product's production, speed-to-market, and efficacy.

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Interview

Voice of resin: Purolite talks US agarose expansion at BIO US 23

With Hayley Crowe

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Interview

Life Science Knowledge Hub Interview Felix Solamo

Felix shares how Purolite's Field Applications team has the capabilities to support our customers across Asia, Europe, and North America.

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Literature

Purolite™ Praesto™ Jetted A50 HipH Data File

Data File

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Interview

Meet the Team: Applications

Video

Hear from two members of our Applications team, as they discuss the benefits of open collaboration between Purolite Healthcare & Life Sciences and its customers.

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Literature

Purolite™ Praesto™ Jetted A50 HipH IFU

Instructions For Use

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Interview

Meet the Team: R&D

Video

Hear from the team as they discuss how they help our customers solve their challenging and complex requirements.

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Webinar

Bioprocessing Educational Series

Dive into cutting-edge content designed to enhance your understanding of the latest industry trends, technologies, and best practices.

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Interview

Purolite and Alvotech | Partnership in Innovation

Video

Since 2015, Purolite and Alvotech have developed a strong partnership, fostered by a shared goal of improving the accessibility of essential biologic medicines.

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Literature

Purolite™ Praesto™ Jetted A50 HipH Column Packing Instructions

Column Packing Instructions

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Literature

Process intensification in mAb capture using an innovative, high capacity PrA resin in batch operation

Scientific Poster

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Interview

Jetting Technology

Video

Hear from the team as they discuss what is jetting technology and how is it beneficial for our customers?

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Literature

Purolite™ Praesto™ Jetted A50 Data File

Data File

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Interview

CPHI: An Interview with Felix Solamo

Felix discusses how Puroilte Praesto HipH jetting technology is helping companies meet the growing market demand for innovative bioprocessing resins and the need to safeguard supply chain security.

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Literature

Purolite™ Praesto™ Jetted A50 Column Packing Instructions

Column Packing Instructions

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Literature

Adapting to Supply Chain Issues Surrounding Antibody-based Therapy Production

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Interview

BIO US 23: An Interview with Aaron Moulin

Discussing Purolite™ Praesto™ Jetted A50 HipH and Ecolab investment,

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Literature

Purolite™ Praesto™ SP/Q Data File

Data File

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Literature

Purolite™ Praesto™ SP/Q Column Packing Instructions

Column Packing Instructions

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Literature

Purolite™ Praesto™ SP/Q Product Brochure

Product Brochure

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Literature

Purolite™ Praesto™ AP+80 Brochure

Product Brochure

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Literature

Purolite™ Praesto™ AP+80 IFU

Instructions For Use

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