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We look at how agarose chromatography resins have traditionally been manufactured before discussing new innovations in manufacturing.
Are you looking for ways to improve your current downstream mAb purification process? You probably haven't considered how the manufacture of your chromatography resin is having an impact. The manufacturing technique used to produce the most commonly-used agarose chromatography resins in the industry hasn't changed since the early 1960s. That's almost 60 years of no innovation in an industry that is struggling to reduce the bottlenecks in downstream processing. But there is a solution.
At Purolite Life Sciences, we have developed an innovative new resin manufacturing method designed to meet the needs of future chromatography processes by creating agarose chromatography resins with uniform particle sizes. But what does that mean for you as the end-user? And what are the benefits of this new manufacturing method for your applications?
In this blog post we look at how agarose chromatography resins have traditionally been manufactured before discussing new innovations in manufacturing that will enhance your separation and purification processes.
Main Benefits of Uniform Particle Sizes in Column Packing include::
Innovations to resin manufacture, such as Jetting, mean uniform particle size protein A agarose-based resins are available for the first time, offering a multitude of process benefits whilst improving cost-efficiencies when compared to alternative resin products. In order to meet industry demands for improved productivity and reduced cost of goods, as well as address ever-increasing upstream titres, resins that perform more efficiently within the same manufacturing footprint are a necessity.