Bioprocessing

Accelerate your biologic
drug development with 
Purolite™ chromatography resins.

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mAb & protein purification
mAb & protein purification
Overview Products
Products
Affinity Chromatography Resins
Affinity Chromatography Resins
Overview Purolite™ DurA™ Cycle A50 Purolite™ Praesto™ 70 CH1 Purolite™ Praesto™ AP+ Platform Purolite™ Praesto™ Jetted A50 HipH Purolite™ Praesto™ Jetted A50
IEX Chromatography Resins
IEX Chromatography Resins
Overview Purolite Praesto™ Jetted SP Purolite Praesto™ Jetted Q
Jetting Technology Technical Support
Technical Support
Technical Support
Bioprocessing Applications Laboratory Field Applications Scientists
Resources
Resources
Knowledge Hub Chromatography Column Packing Calculator Throughput and Productivity Calculator

Purification Technologies

As a global leader in resin technology, we develop and manufacture small beads that are used in the most regulated industries in the world to separate, remove or recover very specific elements and compounds.

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Product Types
Product Types
Adsorbents
Adsorbents
Overview Adsorbents for Enzyme Immobilization Adsorbents for Gases and Organic Vapors Adsorbents of Organic Pollutants Citrus Juice Debittering Corn Sweetener Refining Inorganic Salt Separation Using Adsorbents Patulin Removal Polyphenol Recovery
Catalyst Chelation Resins Chromatographic Separation Resins Inert Spacer Polymers Mixed Bed Resins
Mixed Bed Resins
Overview Mixed Bed Nuclear Mixed Bed Ultrapure Water
Shallow Shell™ Resins Strong Acid Cation Resin Strong Base Anion Resin Weak Acid Cation Resin
Weak Acid Cation Resin
Overview Weak Acid Cation Macroporous Weak Acid Cation Porous
Weak Base Anion Resin
Weak Base Anion Resin
Overview Weak Base Anion Gel Weak Base Anion Macroporous
Industries
Industries
Carbon Capture Chemical Processing and Petrochemical Food and Beverage
Food and Beverage
Overview Dairy Flavors Food Ingredients Fruit Juice
Fruit Juice
Overview Citrus Juice Debittering Patulin Removal Polyphenolic Compound Recovery
Gelatin and Collagen Organic Acid Purification Sugar
Sugar
Overview Beet Sugar Refining Cane Sugar Refining
Sweetener
Sweetener
Overview Corn Sweetener Refining
Additional Food and Beverage
Hydrometallurgy Metals Plating Microelectronics Oil and Gas Potable and Groundwater
Potable and Groundwater
Overview Arsenic Nitrate PFAS TOC, Bromide and DBP Perchlorate
Power
Power
Overview Fossil Nuclear Green Hydrogen
Pulp and Paper
Applications
Applications
Adsorption Catalysis Condensate Polishing Demineralization Metal Removal and Recovery Organics Removal Softening Water Purity Solutions

Pharma and Medical

With 40 years of manufacturing expertise and 30 years of regulatory experience, we supply leading separation, purification and extraction technologies to support chromatography applications within the Pharma and Medical space.

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Pharmaceutical
Pharmaceutical
Overview APIs/Excipients Milling Media
Medical Devices and Diagnostics
Medical Devices and Diagnostics
Overview Biofluid Treatment Diagnostics
Nutraceuticals
Nutraceuticals
Overview Dairy Protein Isolation Supplement Ingredients Vitamin Purification

Ecolab

We are a world leader in resin-based separation, purification and extraction technology, that provides sustainable solutions for our environment, businesses and healthcare.

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About
About
About Us
About Us
Overview History
Locations Services Manufacturing Customer Support Research and Development Brands
Brands
CriticalResin™ Macronet™ Microlite™ Purofine™ Puromet™ Puromill™ Puropack™ PuroSorb™ Shallow Shell™ UltraClean™
Environmental Commitment
Resources
Resources
General Information Certifications
Certifications
Product Certifications Quality, Environment, Health and Safety
Terms of Sale Glossary and Definitions Case Studies
News & Events
News & Events
News Blog Webinars
Tools
Tools
Purolite Resin System Modeling (PRSM™) Chromatography Column Packing Calculator Throughput and Productivity Calculator Unit Conversion Calculator
Overview
Literature

Einsatzgebiete

  • Protein Reinigung
  • Mab Aufreiningung

Vorteile

  • exzellente dynamische Bindungskapazitäten für hohe Produktivität und Skalierbarkeit
  • exzellent Druckverlust Performance
  • hohe Auflösungsselektivität
  • exzellente Chemische und physikalische Stabilität
  • Sichere, validierte Versorgung und regulatorische Unterstützung

Behördliche Genemigungen

  • Manufactured under GMP conditions
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PRODUCT BROCHURE

Purolite Praesto SP/Q Data File

Typische physikalische & chemische Eigenschaften:

Matrix Cross-linked agarose
Funktionelle Gruppe CH2N+C+(CH3)3
Ionische Kapazität - gemittelt 0.09 - 0.18 mmol Cl⁻/ml
Average particle size (d50ᵥ), μm 90 µm
Flow velocity Up to 550 cm/h (20 x 20 cm)
Binding Capacity mg/mL Resin at 6’ Residence Time ≥50 mg BSA ml
Operating pH Stability (Short Term) 2 - 14
Operating pH Stability (Long-Term) 2 - 12
Working Temperature 4 - 30 Grad Celsius
chemische Stabilität All commonly used aqueous buffers. 1M NaOH, 8M urea, 6M guanidine hydrochloride, 30% isopropanol and 70% ethanol
Vermeiden Oxidising agents, anionic detergents
empfohlene Lagerung 20% ethanol at 4 – 30 °C