Find the perfect Ecolab
resin for your monoclonal
antibody purification needs.
As a global leader in resin technology, we develop and manufacture small beads that are used in the most regulated industries in the world to separate, remove or recover very specific elements and compounds.
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With 40 years of manufacturing expertise and 30 years of regulatory experience, we supply leading separation, purification and extraction technologies to support chromatography applications within the Pharma and Medical space.
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We are a world leader in resin-based separation, purification and extraction technology, that provides sustainable solutions for our environment, businesses and healthcare.
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This joint webinar, presented by Bionova Scientific and Ecolab Life Sciences, explores practical strategies for addressing purification challenges in complex biologics. The session highlights the performance of Purolite™ Praesto™ Jetted A50 HipH resin, showcasing its ability to deliver high host cell protein clearance and support milder elution conditions - key advantages for downstream scientists working with monoclonal and bispecific antibodies.
This application note explores how Praesto Jetted A50 HipH resin can help address host cell protein (HCP) challenges in monoclonal antibody purification. It presents data showing up to 8.6X improvement in HCP removal compared to conventional protein A resins, achieved under milder elution conditions that may reduce aggregation risks. For scientists working to enhance product purity and process consistency, this application note offers useful insights into optimizing resin performance.
Eluting at a higher pH improves product quality, reduces impurities, and enhances viral clearance compared to standard methods. This approach also maintains high yield and stability for pH-sensitive molecules, making it ideal for advanced antibody purification.
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Discover how a global pharma team doubled their productivity and increased product yield by up to 130% using a single-step protein purification process. This case study reveals how switching to an innovative resin platform not only improved purity and sustainability, but also saved significant time and resources.
Through the benefit of a mild pH elution, Praesto Jetted A50 HipH delivers increased drug yield, when compared with a traditional protein A resin
The wider pH elution window of Praesto Jetted A50 HipH delivers minimized process impurities & aggregation through the purification process – helping you confidently deliver your final drug product
Universal mild pH binding allows development of a platform approach to complex molecule purification
Enables a move from a three-step to a two-step purification workflow by delivering high yield and purity for even the most sensitive of molecules
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Learn how operating at a milder elution pH during monoclonal antibody purification can minimize protein aggregation and preserve product yield, without compromising viral clearance efficiency. This application note compares innovative chromatography resins and demonstrates how you can achieve superior viral reduction while optimizing process conditions for sensitive molecules.
Ecolab’s HipH resin is engineered to deliver robust performance under elevated pH conditions, making it ideal for applications requiring enhanced impurity clearance and process flexibility. Its unique design supports milder elution profiles while maintaining high binding capacity, helping downstream scientists reduce aggregation risks and improve overall product purity. Explore how HipH can support your purification goals.
