New Product

DurA Cycle A50
Driving innovation and performance while
reducing cost of goods.

Learn More
mAb & protein purification
mAb & protein purification
Overview Products
Products
Affinity Chromatography Resins
Affinity Chromatography Resins
Overview Purolite DurA Cycle A50 Purolite Praesto™ 70 CH1 Purolite Praesto™ AP+80 Purolite Praesto™ Jetted A50 HipH Purolite Praesto™ Jetted A50
IEX Chromatography Resins
IEX Chromatography Resins
Overview Purolite Praesto™ Jetted SP Purolite Praesto™ Jetted Q
Jetting Technology Technical Support
Tools & Services
Tools & Services
Knowledge Hub Chromatography Column Packing Calculator Throughput and Productivity Calculator Field Application Services

Purification Technologies

As a global leader in resin technology, we develop and manufacture small beads that are used in the most regulated industries in the world to separate, remove or recover very specific elements and compounds.

Learn More
Product Types
Product Types
Adsorbents
Adsorbents
Overview Adsorbents for Enzyme Immobilization Adsorbents for Gases and Organic Vapors Adsorbents of Organic Pollutants Citrus Juice Debittering Corn Sweetener Refining Inorganic Salt Separation Using Adsorbents Patulin Removal Polyphenol Recovery
Catalyst Chelation Resins Chromatographic Separation Resins Inert Spacer Polymers Mixed Bed Resins
Mixed Bed Resins
Overview Mixed Bed Nuclear Mixed Bed Ultrapure Water
Shallow Shell™ Resins Strong Acid Cation Resin Strong Base Anion Resin Weak Acid Cation Resin
Weak Acid Cation Resin
Overview Weak Acid Cation Macroporous Weak Acid Cation Porous
Weak Base Anion Resin
Weak Base Anion Resin
Overview Weak Base Anion Gel Weak Base Anion Macroporous
Industries
Industries
Carbon Capture Chemical Processing and Petrochemical Food and Beverage
Food and Beverage
Overview Dairy Flavors Food Ingredients Fruit Juice
Fruit Juice
Overview Citrus Juice Debittering Patulin Removal Polyphenolic Compound Recovery
Gelatin and Collagen Organic Acid Purification Sugar
Sugar
Overview Beet Sugar Refining Cane Sugar Refining
Sweetener
Sweetener
Overview Corn Sweetener Refining
Additional Food and Beverage
Hydrometallurgy Metals Plating Microelectronics Oil and Gas Potable and Groundwater
Potable and Groundwater
Overview Arsenic Nitrate PFAS TOC, Bromide and DBP Perchlorate
Power
Power
Overview Fossil Nuclear Green Hydrogen
Pulp and Paper
Applications
Applications
Adsorption Catalysis Condensate Polishing Demineralization Metal Removal and Recovery Organics Removal Softening Water Purity Solutions

Pharma and Medical

With 40 years of manufacturing expertise and 30 years of regulatory experience, we supply leading separation, purification and extraction technologies to support chromatography applications within the Pharma and Medical space.

Learn more
Pharmaceutical
Pharmaceutical
Overview APIs/Excipients Milling Media
Medical Devices and Diagnostics
Medical Devices and Diagnostics
Overview Biofluid Treatment Diagnostics
Nutraceuticals
Nutraceuticals
Overview Dairy Protein Isolation Supplement Ingredients Vitamin Purification

Purolite Resins

We are a world leader in resin-based separation, purification and extraction technology, that provides sustainable solutions for our environment, businesses and healthcare.

Learn More
About
About
About Us
About Us
Overview History
Locations Services Manufacturing Customer Support Research and Development Brands
Brands
CriticalResin™ Macronet™ Microlite™ Purofine™ Puromet™ Puromill™ Puropack™ PuroSorb™ Shallow Shell™ UltraClean™
Environmental Commitment
Resources
Resources
General Information Certifications
Certifications
Product Certifications Quality, Environment, Health and Safety
Terms of Sale Glossary and Definitions Case Studies
News & Events
News & Events
News Blog Webinars
Tools
Tools
Purolite Resin System Modeling (PRSM™) Unit Conversion Calculator
Praesto implemented into FDA-approved process / News / purolite

Purolite® Protein A chromatography resin implemented into FDA-approved commercial manufacturing of monoclonal antibody treatments

Purolite Ltd., Cardiff, South Wales - Purolite Ltd., a leading manufacturer of resin-based separation, purification and extraction technologies, today announces that Praesto® Jetted A50, an agarose-based Protein A chromatography resin, has been incorporated into the commercial manufacturing process of an FDA-approved monoclonal antibody treatment by one of the world’s leading contract manufacturing organizations.

Praesto resins are an integral technology used by biopharmaceutical developers for the purification of modern medicines for the treatment of cancer, rheumatoid arthritis, dementia and diabetes. Praesto Jetted A50, launched in April 2018, is Purolite’s ‘best-in-class’ Protein A chromatography resin, utilizing a patented, ‘Jetting’ manufacturing technology for uniform resin beads, a highly desirable characteristic for chromatographic applications.

Chris Major, Global Sales and Marketing Director for the Agarose business, comments, “This is another milestone and a proud achievement for Purolite. Praesto Jetted A50 is the only commercially available Protein A resin to offer uniform beads, a feat only achievable through Purolite’s proprietary Jetting technology. Praesto resins are currently incorporated into over 200 PI – PIII clinical trials and resin screening projects globally, and we supply 10 of the world’s largest biopharmaceutical developers and CMOs. For major global organizations to be recognizing and adopting the extensive benefits of Jetting less than two years after launch is a testament to our commitment and success in bringing forward-thinking, practical antibody purification solutions into what was previously a stagnant marketplace.
Purolite has invested over $150 million into a global innovation program in recent years, including doubling the production capacity of our Jetting technology to facilitate growing demand. With this expansion we look forward to continuing to meet customer requirements for improved security of supply, reduced lead times and high-performance of modern Protein A resins.”

To view our Praesto Jetted A50 range, click here.