Bioprocessing
Accelerate your biologic drug development with Praesto®
chromatography resins.

Accelerate your biologic drug development with Praesto®
chromatography resins.
As the global leader in resin technology, we develop and manufacture small beads that are used in the most regulated industries in the world to separate, remove or recover very specific elements and compounds.
Learn MoreWith 40 years of manufacturing expertise and 30 years of regulatory experience, we supply leading separation, purification and extraction technologies to support chromatography and biocatalysis applications in healthcare and life sciences.
Learn moreWe are the world leader in resin-based separation, purification and extraction technology, that provides sustainable solutions for our environment, businesses and healthcare.
Learn MoreA patented process for uniform, customizable Protein A and Ion Exchange resins
Наши всегда готовые к работе группы технической поддержки и обслуживания делают дополнительный шаг, чтобы стать вашим самым надежным ресурсом. Мы здесь для вас.
Jetting technology is a patented, continuous manufacturing process for producing chromatographic resin beads with a narrow, uniform particle size distribution.
Purolite is the only resin supplier to manufacture process-scale volumes of copolymer and agarose resin beads with uniform particle sizes. The uniform resin beads provide a more consistent chromatographic process.
Our non-solvent jetting produces a 100% yield versus the traditional batch emulsification method of resin manufacture, with results as low as 40% yield.
Jetting is being utilized by leading biopharmaceutical developers all over the world to streamline their mAb processes.
Advantages:
Jetting technology operates with two different processes, depending on the particle size needed. The first Purolite jetting process – membrane or ‘can’ jetting – entails using a membrane with very small, discrete orifices, through which the polymer is passed. This device is capable of producing uniform particle size chromatographic resins from ~15 to 250 micron. Cooled, and then hardened, the beads are then collected in a vessel. The process can run continuously.
Subsequent process steps (cross-linking, derivatization) are similar to those for emulisified beads.
This process is unique to Purolite, and an innovation in the manufacture of agarose beads. There are significant opportunities to adjust the process to account for variability in regards to incoming materials, to ensure a highly consistent product with respect to particle size distribution.
The second process, plate jetting, utilises a plate with many precisely engineered holes, through which the resin polymer is passed. Uniform particle size chromatographic resins of ~150 to >1,000 micron can be produced using this method.
Jetting technology produces a much tighter distribution of particles (UC < 1.3) than traditional batch wise emulsification technologies (UC < 1.9). The time-consuming screening step found in batch wise emulsification is not required in the Jetting process, greatly reducing lead times.
Jetting technology is used to manufacture select products in our ranges of agarose and synthetic chromatography resins, including Praesto® Jetted A50, Praesto® Jetted Q35, Praesto® Jetted SP35 and Chromalite®.
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