Overview

CBD Resources

Product Performance

Chromalite vs. Silica

Case Study

CBD Purification - Reverse Phase Chromatography Resins

New to the CBD industry or scaling-up production?

Purolite's resin technology can maximize your yield with reverse phase chromatography to separate CBD in high purity from the cannabis extract. Purolite's Chromalite® can help to ensure compliance with industry regulations while increasing profits.

As a low-temperature alternative to distillation, chromatography can help you better manage the final quality and characteristics of your natural cannabinoid blend. Our pharmaceutical-grade resins are the perfect solution to achieving consistency for your CBD extract with less than 0.3% THC. And compared to C18 silica-based alternatives, Chromalite resins' high performance provides cost-efficiencies over time.

Still not convinced? Test for Yourself

Pre-Packed 200 mL Columns - Order today

Ideal for rapid lab-scale testing and feasibility studies
Construction Material - Polypropylene
Media Volume - 200 mL
Maximum Operating Pressure - 1.3 MPa (200 psi)
Recommended Flow Rate - 60 mL/min (max 150 mL/min)

Additional applications for CBD manufacturing:

CBD Resources

The Highs and Lows of Cannabinoid Purification On-Demand Webinar

Purolite CBD Purification
Choosing a Better Chromatographic Process for CBD Manufacturing

BROCHURE

Purolite CBD Purification

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Q&A

Choosing a Better Chromatographic Process for CBD Manufacturing

Product Performance

Low Porosity - High purity. Great for CBD isolate or individual cannabinoid isolation
PCG600M*
PCG600C**

Medium Porosity - Good blend of yield and purity
PCG900M*
PCG900C**

High Porosity - High yield. Great for full spectrum CBD
PCG1200M*
PCG1200C**

* 75 micron mean diameter, used to prepare chromatography operation
** 150 micron mean diameter, used in industrial scale, i.e., simulated moving bed or other continuous, high flow chromatography operation

Chromalite vs. Silica

Chromalite® resins demonstrate significantly reduced breakdown over time when compared to equivalent competitor silica resins. They are stable for a long lifetime and suitable for harsher usage conditions.

Chromalite Mechanical Stability
When compared to silica-based alternatives, Chromalite chromatographic resins offer a simple, high performance and cost-efficient method to separate THC from CBD, improving the purity of CBD extracts.

The stability and physical strength of Chromalite resins mean they require replacement less often than traditional silica chromatography media as they can be utilized in process conditions where silica is often damaged or dissolved.

Successful Implementation of Chromalite™ Media to Produce THC-free CBD Oil

Chromalite Performance By Product

Chromalite's Mechanical Stability vs. Silica

Cannabinoid Production (CBD) Produtos por aplicação

Reversed Phase Chromatography

PCG1200C

Poliestireno Adsorvente Macroporoso Non-functionalized Resin, 100 - 200 µm, 300 - 500Å pores

PCG1200F

Poliestireno Adsorvente Macroporoso Non-functionalized Resin, 20 - 50 µm, 300 - 500Å pores

PCG1200M

Poliestireno Adsorvente Macroporoso Non-functionalized Resin, 50 - 100 µm, 300 - 500Å pores

PCG600C

Poliestireno Adsorvente Macroporoso Non-functionalized Resin, 100 - 200 µm, 75 - 150Å pores

PCG600F

Poliestireno Adsorvente Macroporoso Non-functionalized Resin, 20 - 50 µm, 75 - 150Å pores

PCG600M

Poliestireno Adsorvente Macroporoso Non-functionalized Resin, 50 - 100 µm, 75 - 150Å pores

PCG900C

Poliestireno Adsorvente Macroporoso Non-functionalized Resin, 100 - 200 µm, 150 - 300Å pores

PCG900F

Poliestireno Adsorvente Macroporoso Non-functionalized Resin, 20 - 50 µm, 150 - 300Å pores

PCG900M

Poliestireno Adsorvente Macroporoso Non-functionalized Resin, 50 - 100 µm, 150 - 300Å pores