Cost-effective, greener manufacturing: Using immobilized enzymes in industrial biocatalysis

28 sty 2021 /

In this article we look at the use of immobilized enzymes in industrial manufacture and the benefits they offer to create a more eco-sustainable and efficient process.

Why our US manufacturing expansion is important for the Protein A chromatography resin market

20 sty 2021 /

In this article we look at the key industry drivers and our own commitment to secure supply to explain why our US manufacturing expansion is important, and what it will mean for our customers.

Agarose End Of Year Update 2020

14 sty 2021 /

An end of year business update from Global Sales and Marketing Director Chris Major of the Purolite Life Sciences agarose division.

Application Insight | Cocoa Butter Analogues

24 lis 2020 /

Discover how our enzyme immobilization resins are used in the creation of cost-effective cocoa butter equivalents (CBE) in the food industry.

What value does brand loyalty have in a time of crisis if you can’t source your Protein A?

17 lis 2020 /

In this article We look at the effects of customer loyalty during the pandemic when measured against the importance of effective supply chain management for the global biopharma industry.

The impact of protein A resin on ensuring an efficient and reliable continuous downstream process in mAb purification

21 paź 2020 /

With protein A resins being a significant cost in the manufacture of these mAb products, we review the true impact of protein A resin on ensuring an efficient and reliable continuous downstream process in mAb purification.

Application Insight | Sofosbuvir

20 sie 2020 /

Discover how immobilized enzymes are used for the production of Sofosbuvir, a widely-used antiviral treatment for hepatitis C.

Meet the Purolite Team: Patrick Gilbert

10 sie 2020 /

Learn more about the amazing team behind our revolutionary protein A resin range, starting with R&D Manager Patrick Gilbert.

5 things you need to know about Chromalite® MIDA

15 lip 2020 /

Introducing Chromalite® MIDA: IMAC (immobilized metal affinity chromatography) resin designed to selectively capture His-tagged enzymes for biocatalytic processes.

Why does uniform particle size matter in agarose chromatography resins?

7 lip 2020 /

In this blog post we look at how agarose chromatography resins have traditionally been manufactured before discussing new innovations in manufacturing

2020 - Agarose, The Year So Far

2 lip 2020 /

Mid year update from Global Sales and Marketing Director Chris Major of the Purolite Life Sciences agarose division.

How to Reduce Buffer Consumption

6 kwi 2020 /

In this article, we analyse the growing industry need to reduce buffer consumption in the purification of proteins and monoclonal antibodies.

Using Chromatography to purify Cannabidiol

2 kwi 2020 /

We look at the importance of chromatographic purification in the production of medical-grade cannabidiol (CBD) for modern therapeutics.

7 Regulatory Considerations when Sourcing an Alternative Resin Supplier

19 lut 2020 /

Important regulatory considerations when sourcing a new resin supplier.

The Importance of Dynamic Binding Capacity in mAb Purification

23 sty 2020 /

There is now greater pressure on downstream purification processes to meet the demand from increased cell titers. But how can you meet this demand without negatively impacting your manufacturing footprint and process economy?

Industrial Adsorbents Presentation

22 sty 2020 /

A presentation by Fred Ghanem looking at the two new product ranges of industrial adsorbents from Purolite Life Sciences.

Replacing the 'art' of column packing with science

20 lis 2019 /

A state-of-the-art column packing training facility, with best-in-class pilot and process-scale equipment for optimal MAb bioprocessing.

Laboratory Scale Columns for Performance Screening

30 paź 2019 /

An analysis between two different agarose-based chromatography resins, packed as per manufacturer’s instructions into two commonly-used columns at smaller scales

The Praesto® Agarose Production Facility | A Year On...

27 wrz 2019 /

Celebrating the 1 year anniversary of one of the world's largest agarose resin manufacturing sites

Why Agarose?

31 lip 2019 /

For the purposes of chromatography, agarose is widely considered the best material available for the protein purification resins.

Explaining Volume and Number Particle Size Distribution in Resins

10 lip 2019 /

An explanation of volume and number particle size distribution in chromatography resins.

Expanding the Frontiers of Biocatalysis

17 cze 2019 /

Discover how to optimise processes using modern, robust, high performing enzyme carriers

Purolite Life Sciences - providing regulatory support in life sciences

13 cze 2019 /

The regulatory environment is ever-changing, driven by increasing regulatory requirements, increasing development costs and times, and market pressures impacting pharmaceutical and food industries.

R&D Update - Q3 - 2019 - Praesto XS

4 cze 2019 /

Join us for round-up of key R&D updates each quarter.

Packing for Efficiency

24 maj 2019 /

In order that the purification process and the final product are robust and secure, it is vital that chromotography columns are properly packed and qualified in a reasonable time frame.

The Future in Protein A Affinity Matrix Design | Part Three

8 maj 2019 /

Praesto® Jetted A50 resin is the first product designed by combining the new technology for continuous manufacturing of agarose beads with a novel alkaline-stable Protein A ligand.

The Future in Protein A Affinity Matrix Design | Part Two

29 kwi 2019 /

With the continued growth and therapeutic commercial importance of mAb production, the availability of high-quality agarose resins is critical.

The Future in Protein A Affinity Matrix Design | Part One

23 kwi 2019 /

Protein A affinity chromatography continues to be the preferred method for commercial purification of antibodies because of its high selectivity and robust resin performance over repeated purification cycles.

Case Study CalB immo Plus Immobilized Enzyme

16 kwi 2019 /

In addition to a complete range of enzyme carriers - Lifetech™ ECR, the Purolite Life Sciences team has developed ready-to-use immobilized enzymes for a variety of applications in industry. The immobilized enzymes developed at Purolite cover different groups such as transferases, hydrolases, isomerases etc.

What is Jetting?

22 lut 2019 /

What can our jetting process do for you? Purolite Life Sciences uses Jetting to produce both copolymer and agarose-based resins, and are the only resin supplier in the world with the ability to manufacture jetted agarose products.

Discover the Chromalite® resins range

26 paź 2018 /

Purolite has developed the widest range of synthetic polymers for all of your purification and chromatography needs. For any separation by reverse-phase (RP) or ion exchange (IEX); our Chromalite® range has a product for your needs.

Purolite Corporation implements Ideagen’s software

11 wrz 2018 /

Purolite Life Sciences has adopted software from Ideagen as it looks to enhance quality and compliance processes at its new manufacturing, research, development and quality centre of excellence site based in South Wales.

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