With protein A resins being a significant cost in the manufacture of these mAb products, we review the true impact of protein A resin on ensuring an efficient and reliable continuous downstream process in mAb purification.
Discover how immobilized enzymes are used for the production of Sofosbuvir, a widely-used antiviral treatment for hepatitis C.
Learn more about the amazing team behind our revolutionary protein A resin range, starting with R&D Manager Patrick Gilbert.
Introducing Chromalite® MIDA: IMAC (immobilized metal affinity chromatography) resin designed to selectively capture His-tagged enzymes for biocatalytic processes.
In this blog post we look at how agarose chromatography resins have traditionally been manufactured before discussing new innovations in manufacturing
Mid year update from Global Sales and Marketing Director Chris Major of the Purolite Life Sciences agarose division.
In this article, we analyse the growing industry need to reduce buffer consumption in the purification of proteins and monoclonal antibodies.
We look at the importance of chromatographic purification in the production of medical-grade cannabidiol (CBD) for modern therapeutics.
Important regulatory considerations when sourcing a new resin supplier.
There is now greater pressure on downstream purification processes to meet the demand from increased cell titers. But how can you meet this demand without negatively impacting your manufacturing footprint and process economy?
A presentation by Fred Ghanem looking at the two new product ranges of industrial adsorbents from Purolite Life Sciences.
End of Year wrap up from Global Sales and Marketing Director Chris Major of the Purolite Life Sciences Agarose division.
A state-of-the-art column packing training facility, with best-in-class pilot and process-scale equipment for optimal MAb bioprocessing.
An analysis between two different agarose-based chromatography resins, packed as per manufacturer’s instructions into two commonly-used columns at smaller scales
Celebrating the 1 year anniversary of one of the world's largest agarose resin manufacturing sites
For the purposes of chromatography, agarose is widely considered the best material available for the protein purification resins.
An explanation of volume and number particle size distribution in chromatography resins.
Discover how to optimise processes using modern, robust, high performing enzyme carriers
The regulatory environment is ever-changing, driven by increasing regulatory requirements, increasing development costs and times, and market pressures impacting pharmaceutical and food industries.
Join us for round-up of key R&D updates each quarter.
As we approach the second half of 2019, I wanted to provide a business update with respect to progress of the Agarose Chromatography division of Purolite Life Sciences
In order that the purification process and the final product are robust and secure, it is vital that chromotography columns are properly packed and qualified in a reasonable time frame.
Praesto® Jetted A50 resin is the first product designed by combining the new technology for continuous manufacturing of agarose beads with a novel alkaline-stable Protein A ligand.
With the continued growth and therapeutic commercial importance of mAb production, the availability of high-quality agarose resins is critical.
Protein A affinity chromatography continues to be the preferred method for commercial purification of antibodies because of its high selectivity and robust resin performance over repeated purification cycles.
In addition to a complete range of enzyme carriers - Lifetech™ ECR, the Purolite Life Sciences team has developed ready-to-use immobilized enzymes for a variety of applications in industry. The immobilized enzymes developed at Purolite cover different groups such as transferases, hydrolases, isomerases etc.
Today, Purolite has one of the world’s largest agarose resin manufacturing facilities - producing a range of high flow agarose Protein A chromatography resins specifically designed to give purification performance equal to, or better than, today’s market leading agarose resins.
What can our jetting process do for you? Purolite Life Sciences uses Jetting to produce both copolymer and agarose-based resins, and are the only resin supplier in the world with the ability to manufacture jetted agarose products.
Seeded polymerisation: mono-size, ultra-fine beads for chromatography
As we move ever closer to the end of another successful year, the team at Purolite Life Sciences would like to wish you a happy and prosperous 2019.
With more than 30 years’ experience in the biotech business, along with more than ten patents in the area of resin design and large-scale protein purification, Hans Johannson is the Global Applications manager for Agarose.
Purolite Life Sciences continues to lead the future of chromatography with the expertly-designed Chromalite® M range of methacrylic resins.
Purolite has developed the widest range of synthetic polymers for all of your purification and chromatography needs. For any separation by reverse-phase (RP) or ion exchange (IEX); our Chromalite® range has a product for your needs.
Earlier this month, Purolite Life Sciences attended BioProcess International 2018, part of Biotech Week in Boston.
Purolite Life Sciences has adopted software from Ideagen as it looks to enhance quality and compliance processes at its new manufacturing, research, development and quality centre of excellence site based in South Wales.
2016-10-27 / Wales, UK
Discover Purolite's large-scale UK manufacturing facility for the production of agarose resins for the biologics industry, due for completion in 2017.