DurA Cycle A50
Driving innovation and performance while
reducing cost of goods.
Jako światowy lider w technologii żywic opracowujemy i produkujemy małe kulki, które są wykorzystywane w najbardziej regulowanych gałęziach przemysłu na świecie do oddzielania, usuwania lub odzyskiwania bardzo specyficznych pierwiastków i związków.
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(Obecnie tylko w języku angielskim)
With 40 years of manufacturing expertise and 30 years of regulatory experience, we supply leading separation, purification and extraction technologies to support chromatography and biocatalysis applications in healthcare and life sciences.
Jesteśmy światowym liderem w technologii separacji, oczyszczania i ekstrakcji na bazie żywic, która zapewnia zrównoważone rozwiązania dla naszego środowiska, firm i opieki zdrowotnej.
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Capacity
Purolite Praesto Jetted A50 exhibits high dynamic binding capacities for conventional monoclonal antibodies, up to 70 g/L at a 10-minute residence time. Patented Jetting technology, coupled with the latest protein A technology, allows for high capacity at even low residence times. The resin is uniquely suited to address the demands of modern bioprocessing, from high-titre cell cultures to continuous chromatography formats.
Flow
The uniform particle size and highly cross-linked agarose base bead provides increased surface area without severely impacting pressure flow properties. Purolite Praesto Jetted A50 has excellent flow properties, with up to 200 cm/h achievable in a standard mAb platform process. This has been verified in process scale columns.
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Capacity
Purolite Praesto Jetted A50 HipH exhibits high dynamic binding capacities for conventional monoclonal antibodies, up to 60 g/L at a 6-minute residence time. Patented Jetting technology, coupled with the latest protein A technology, allows for high capacity at even low residence times. The resin is uniquely suited to address the demands of modern bioprocessing, from high-titre cell cultures to continuous chromatography formats.
Flow
The uniform particle size and highly cross-linked agarose base bead provides increased surface area without severely impacting pressure flow properties. Purolite Praesto Jetted A50 HipH has excellent flow properties, with up to 200 cm/h achievable in a standard mAb platform process. This has been verified in process scale columns.
Read the latest paper Evaluation of mild pH elution protein A resins for antibodies and Fc-fusion proteins and find out how Purolite Praesto Jetted A50 HipH is an ideal candidate for a platform protein A resin that provides flexibility for pH-sensitive proteins and stable mAbs, while preserving product quality, recovery, and seamless integration into a downstream process.
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