Praesto AC is a Protein A resin designed for high productivity, cost-effective MAb capture. It combines good capacity, excellent pressure/flow performance and NaOH CIP stability for up to 20 cycles, meeting common requirements for production PI and PII clinical trial materials. Praesto AC can also be used in small scale MAb purification, purification of MAbs for diagnostics, in process development and in pre-clinical processes.

Click here for a scientific paper, benchmarking our Praesto AP Protein A resin, against others on the market. Performed by an independent third party and published by the Journal of Chromatography A.

Główne zastosowania

  • Protein purification (20-500 kDa)
  • MAb Purification

Zalety

  • High productivity
  • High dynamic binding capacity
  • Enhanced pressure/flow performance
  • NaOH CIP stability for up to 20 cycles
  • Secure, validated supply and regulatory support

Zgodność z regulacjami

  • Manufactured under cGMP conditions

Dostępność opakowań

  • Bulk Resin
  • Production-Scale OPUS® Columns
  • OPUS® Robocolumns®
  • OPUS® MiniChrom Columns
  • HT Columns

PODSTAWOWE WŁAŚCIWOŚCI FIZYCZNE I CHEMICZNE:

struktura polimeru Highly cross linked agarose
Appearance Spherical beads
grupa funkcyjna Protein A
Particle Size - µm 85 µm
Dynamic Binding Capacity (min.)- 3 minutes residence time 25 hlgG/ml
Pressure/flow (min.) - at 3 bar in a 2.6 x 20 cm column (pressure-packed at 4 bar) 500 cm/h
pH stability, CIP (short term) 2 - 12
pH stability, working range 3 - 10
Recommended Storage 2 - 8 °C
Recommended Storage 20% ethanol