Praesto Jetted Q35 is an agarose-based, strong anion exchange resin designed for biomolecule purification, including proteins, peptides and oligonucleotides. 

It is manufactured using 'Jetting' - a new, patented method that produces agarose beads with a very narrow particle size distribution. Purolite is the first agarose resin provider to produce process-scale volumes of these uniform particle size beads.

Praesto® Ion Exchange Chromatography Resins - FAQs

Principal Applications

  • MAb Purification
  • Protein purification (20-500 kDa)

Advantages

  • Uniform particle size
  • High capacity
  • Enhanced productivity
  • Enhanced pressure/flow performance
  • Manufactured with reduced environmental impact
  • Secure, validated supply and regulatory support

Regulatory Approvals

  • Manufactured under cGMP conditions

Typical Packaging

  • Bulk Resin
  • Production-Scale OPUS® Columns
  • OPUS® Robocolumns®
  • OPUS® MiniChrom Columns
  • HT Columns

Typical Physical & Chemical Characteristics:

Matrix Cross-linked agarose
Functional Group CH2N+C+(CH3)3
Ionic Capacity, mmol/mL Resin 0.14-0.18
Average Particle Size (d50ᵥ), μm 35
Flow Velocity cm/h at 3 bar in a 2.6 x 20 cm Column (packed at 4 bar) > 150
Binding Capacity mg/mL Resin at 6’ Residence Time > 80 mg/ml BSA
Operating pH Stability (Short Term) pH 2-14
Operating pH Stability (Long-Term) pH 3-13
Working Temperature 4-30°C
Chemical stability All commonly used aqueous buffers, 1M NaOH, 8M urea, 6M guanidine hydrochloride, 30% isopropanol and 70% ethanol
Avoid Oxidizing agents, cationic detergents
Storage 20% ethanol, 4-30°C

The statements, technical information and recommendations contained herein are believed to be accurate as of the date hereof. Since the conditions and methods of use of the product and of the information referred to herein are beyond our control, Purolite expressly disclaims any and all liability as to any results obtained or arising from any use of the product or reliance on such information; NO WARRANTY OF FITNESS FOR ANY PARTICULAR PURPOSE, WARRANTY OF MERCHANTABILITY OR ANY OTHER WARRANTY, EXPRESSED OR IMPLIED, IS MADE CONCERNING THE GOODS DESCRIBED OR THE INFORMATION PROVIDED HEREIN. The information provided herein relates only to the specific product designated and may not be applicable when such product is used in combination with other materials or in any process. Nothing contained herein constitutes a license to practice under any patent and it should not be construed as an inducement to infringe any patent and the user is advised to take appropriate steps to be sure that any proposed use of the product will not result in patent infringement.