Chromalite A860/5952 is ideal for isolation of proteins, especially for proteins from milk and diary products. The charge on the protein is dependent of the working pH, resulting in three situations:

pH = IEP (iso-electric-point) = Protein is neutral
pH <IEP = Protein is positively charged
pH >IEP = Protein is negatively charged

By selecting the right pH conditions, selective adsorption of a protein can be achieved. Optimal protein separation is achieved when the target protein possesses a charge that is opposite to the other proteins in the solution. Under these conditions, protein will selectively adsorb on an IEX resin. A well-known example for this approach is the separation of Lactoferrin from whey using a cation exchanger. A similar approach can be applied to other proteins. Conditions are adjusted in such a way that the target protein possesses a negative charge, while the untargeted proteins are positively charged.

Chromalite A860/5952 is an ideal choice, due to its hydrophilic, protein-compatible matrix. The resin rigidity and particle size also allows packing in industrial columns. 

Principal Applications

  • Protein purification


  • Highly reversible adsorption
  • Excellent resistance to organic fouling
  • Efficient regeneration

Regulatory Approvals

  • Compliant with ResAP(2004) 3
  • Halal
  • Kosher
  • TSE/BSE/GMO free

Typical Packaging

  • 50g
  • 250g
  • 1Kg
  • 2-10Kg
  • 25Kg

Typical Physical & Chemical Characteristics:

Appearance Spherical beads
Functional Group Quaternary Ammonium
Supplied as Wet in Cl- form
Volume capacity (min.) 0.8 eq/l
Weight capacity (min.) 4 eq/Kg
Particle size (90% in Range) 425 - 1200 µm
Total moisture 66 - 72 %
pH limit stability 1 - 14
Optimal storage condition 2 - 20 °C
Ionic Form Cl-
Expiry date (from date of manufacture) 5 years