Chromalite AD1 are  low porous, non functionalised  highly crosslinked polymers in very small and uniform particle size. Chromalite AD1 products are ideal for high pressure reverse phase liquid chromatography (RP-HPLC).  High bead integrity, excellent chemical and physical stability, very low extractibles content, resistance to changes in chemical conditions,good kinetics and excellent selectivity make these products especially suitable for high purity adsorption and chromatographic separations. This series of products are manufactured to a controlled particle size specification for efficient chromatographic column packing. The spherical beads show exceptional batch to batch consistency to enable scale up from laboratory tests, through pilot plant to full plant operation.

Principal Applications

  • Analytical Reverse Phase chromatography (RP-HPLC)
  • Separation of proteins, peptides and oligonucleotides
  • Ideal for biomolecules purification and polishing


  • Highly hydrophobic adsorbent
  • High chemical stability (tolerates all common organic solvents)
  • More robust than silica materials
  • Easy to pack in HPLC columns
  • Regenerable using standard procedures
  • Stable up to 100bar
  • Narrow particle size range

Regulatory Approvals

  • Compliant with FDA regulation 21 CFR 173.65
  • Compliant with ResAP(2004) 3
  • Halal
  • Kosher
  • TSE/BSE/GMO free

Typical Packaging

  • 10g
  • 50g
  • 100g

Typical Physical & Chemical Characteristics:

Appearance White Spherical Beads
Functional Group None
Supplied as Dry in 20% EtOH solution
Surface Area (min.) 500 m²/g
Porosity, Median Pore Diameter 100 - 200 Å
Particle size (90% in Range) 12 - 18 µm
Mean Diameter 13 - 17 µm
Uniformity Coefficient (max.) < 1.15
Total moisture 0 - 5 %
pH limit stability 1 - 14
Optimal storage condition 2 - 20 °C
Expiry date (from date of manufacture) 5 years