Chromalite 10AD2Q is a quaternary ammonium functionalized, highly crosslinked, highly porous polymer. Available in small, uniform particle sizes, Chromalite 10AD2Q is ideal for IEX high pressure liquid chromatography (IEX-HPLC).  The spherical beads show exceptional batch-to-batch consistency, enabling simple scale-up from laboratory analyses through to full-scale plant operation. Chromalite AD is manufactured using our patented seeding technology.

Equivalent to Mono Q®


Principal Applications

  • Analytical Reverse Phase chromatography (RP-HPLC)
  • Separation of proteins, peptides and oligonucleotides
  • Ideal for biomolecules purification and polishing


  • Highly hydrophobic
  • High chemical stability
  • More robust than silica materials
  • Easy packing for HPLC application
  • Efficient regeneration
  • Narrow particle size

Regulatory Approvals

  • Compliant with FDA regulation 21 CFR 173.65
  • Compliant with ResAP(2004) 3
  • Halal
  • Kosher
  • TSE/BSE/GMO free

Typical Packaging

  • 10g
  • 50g
  • 100g

Typical Physical & Chemical Characteristics:

Appearance White Spherical Beads
Supplied as Dry in 20% EtOH solution
Functional Group None
pH Limit Stability 1 - 14
Functional Group Quaternary amine
Ionic Form None
Appearance White to off white spherical beads
Surface Area (min.) 500 m²/g
Porosity, Median Pore Diameter 200 - 300 Å
Particle size (90% in Range) 7 - 13 µm
Mean Diameter 8 - 12 µm
Uniformity Coefficient (max.) < 1.15
Total moisture 0 - 5 %
Optimal storage condition 2 - 20 °C
Expiry date (from date of manufacture) 5 years
Column material Stainless steel