Polystyrene is the most common core resin used in solid phase peptide chemistry, due to its chemical stability, compatibility with the majority of organic solvents, and of course cost and availability

PuroSynth™ supports for Solid Phase Peptide Synthesis (SPPS) are made of polystyrene containing 1% divinylbenzene (DVB) as a crosslinking agent. This polystyrene resin is insoluble in all common solvents, it swells well in most organic solvents and is supplied as uniform spherical beads.

One of the key features of PuroSynth™ products is the narrow particle size distribution due to the unique manufacturing process. ‘Jetting’ - the Purolite® patented manufacturing process, allows the production of uniform particle size, with low uniformity coefficient and high productivity in a continuous mode. This enables a more economic and environmentally friendly (reduced waste) process, than classic batch emulsion polymerization.

The key advantages of PuroSynth™ resin:

  • Complete range of products for Fmoc and Boc chemistry
     
  • Narrow particle size distribution (manufactured by jetting)
     
  • Large scale batches (500+ Kg per batch)
     
  • Performances equivalent to, or better than, main products
     
  • Made in the EU in an ISO 9001:2008 and ISO 18001:2007 certified facility
     
  • Controlled residual organics in the resins, leading to higher purity of final peptide Regulatory Support Files (RSF) available

Solid Phase Peptide Synthesis Products by Application