Praesto® Resins in OPUS® Columns

All of our Praesto® resins are available pre-packed into Repligen OPUS® columns.

The Praesto® range includes a selection of affinity chromatography and ion exchange chromatography agarose resins, delivering exceptional results from capture to high-resolution polishing steps.

In this fast-paced environment, quick turnaround and optimized facility utilization are essential. By utilizing pre-packed, pre-qualified Praesto® formats, savings are maximized by avoiding time consuming operations such as packing, packing evaluation and cleaning procedures.

Additionally, investment costs for packing hardware, as well as the risks associated with packing failures and microbial contamination, are significantly reduced.

The OPUS® Range

OPUS® Columns are designed for use in downstream automated parallel chromatography, bench-scale resin screening, process development, and sample preparation.

Praesto® resins are available packed into various columns within the OPUS® range, such as:

Robocolumn®

For HTPD work, Praesto® resins are available in RoboColumn® volumes of 8 x 200 μL and 8 x 600 μL. They are 100% quality checked for HETP and asymmetry.

OPUS® RoboColumns® provide a small bed volume for fast results and minimal sample and buffer consumption, offering both very high reproducibility and very good scalability.

This column format is designed for use with robotic workstations for HTPD work. They are packed and delivered ready for use. 

Individual laser labelling ensures traceability to corresponding resin and column performance data. The columns are made of biocompatible polypropylene.

Minichrom™

OPUS® MiniChrom pre-packed columns provide a small bed volume for fast results and minimal sample and buffer consumption, as well as convenience in media screening and easy, direct connection to chromatography systems. They are 100% quality checked for HETP and asymmetry.

Process development is streamlined by using OPUS® MiniChrom columns, pre-packed with your chosen Praesto® high flow Affinity or Ion Exchange resin, enhancing both time and cost savings of mAb platform processing.

OPUS® MiniChrom columns are designed for process development and parameter screening, as well as for small scale purification or sample preparation. MiniChrom columns are packed and delivered ready for use.

The columns are made of biocompatible polypropylene.

OPUS® 5 - 80R COLUMNS

In response to the need to scale up chromatography processes, Repligen offers the largest pre-packed columns for the bioprocess industry. OPUS® 45R,  60R and 80R columns are the first pre-packed columns designed to meet the chromatography requirements of larger 1000L and 2000L single-use bioreactors.

ADVANTAGES

  • Easily configured for bed height, resin, and application
  • Seamless and linear scale-up from smaller OPUS® columns
  • Complete documentation package for GMP use
  • Significant time and cost savings compared to conventional column technology