Oligonucleotide Purification Resins

Oligonucleotide synthesis results in the formation of impurities, making efficient chromatographic purification a key processing step to obtain the purity required for pharmaceutical use. Our chromatographic resins are designed for optimal separation and purification performance at HPLC to manufacturing scales. Purolite-patented technology for monodisperse resin beads enables you to achieve your target purity and yields.

Our resins are ideal for applications requiring:

  • Adsorption
  • Reverse phase chromatography
  • HPLC (bulk or pre-packed)
  • Solid phase extraction
  • Ion exchange chromatography
We have a range of chemistries functionalized onto Agarose, Styrene/DVB or Methacrylic polymers to suit your process requirements. (how to select the optimal base matrix).

View our resin ranges by application below.

Oligonucleotide Purification Products by Application


Solid Phase Extraction