Protein and MAb Purification Resins

We have developed the Praesto® line of agarose chromatography resins specifically to provide exceptional protein purification performance from Protein A affinity capture to high-resolution ion exchange polishing steps.

A high flow agarose base matrix is the back bone of each Praesto resin, with a porosity and pore structure ideal for the purification of large, complex biologics such as monoclonal antibodies.

How do Protein and MAb Purification Resins work?

Affinity chromatography is a method of separating proteins based on a highly specific, reversible interaction between an individual or group of proteins, and a suitable ligand attached to a chromatographic matrix.

Ion Exchange chromatography is used to separate molecules based on their net surface charge.

Anion exchange chromatography uses a positively charged ion exchange resin with an affinity for molecules having net negative surface charges.

Cation exchange chromatography uses a negatively charged ion exchange resin with an affinity for molecules having net positive surface charges.

 

Protein and MAb Purification Products by Application