Cost-effective, greener manufacturing: Using immobilized enzymes in industrial biocatalysis

Jan 28, 2021 /

In this article we look at the use of immobilized enzymes in industrial manufacture and the benefits they offer to create a more eco-sustainable and efficient process.

Agarose End Of Year Update 2020

Jan 14, 2021 /

An end of year business update from Global Sales and Marketing Director Chris Major of the Purolite Life Sciences agarose division.

Application Insight | Cocoa Butter Analogues

Nov 24, 2020 /

Discover how our enzyme immobilization resins are used in the creation of cost-effective cocoa butter equivalents (CBE) in the food industry.

What value does brand loyalty have in a time of crisis if you can’t source your Protein A?

Nov 17, 2020 /

In this article We look at the effects of customer loyalty during the pandemic when measured against the importance of effective supply chain management for the global biopharma industry.

The impact of protein A resin on ensuring an efficient and reliable continuous downstream process in mAb purification

Oct 21, 2020 /

With protein A resins being a significant cost in the manufacture of these mAb products, we review the true impact of protein A resin on ensuring an efficient and reliable continuous downstream process in mAb purification.

Application Insight | Sofosbuvir

Aug 20, 2020 /

Discover how immobilized enzymes are used for the production of Sofosbuvir, a widely-used antiviral treatment for hepatitis C.

Meet the Purolite Team: Patrick Gilbert

Aug 10, 2020 /

Learn more about the amazing team behind our revolutionary protein A resin range, starting with R&D Manager Patrick Gilbert.

5 things you need to know about Chromalite® MIDA

Jul 15, 2020 /

Introducing Chromalite® MIDA: IMAC (immobilized metal affinity chromatography) resin designed to selectively capture His-tagged enzymes for biocatalytic processes.

Why does uniform particle size matter in agarose chromatography resins?

Jul 7, 2020 /

In this blog post we look at how agarose chromatography resins have traditionally been manufactured before discussing new innovations in manufacturing

2020 - Agarose, The Year So Far

Jul 2, 2020 /

Mid year update from Global Sales and Marketing Director Chris Major of the Purolite Life Sciences agarose division.

How to Reduce Buffer Consumption

Apr 6, 2020 /

In this article, we analyse the growing industry need to reduce buffer consumption in the purification of proteins and monoclonal antibodies.

Using Chromatography to purify Cannabidiol

Apr 2, 2020 /

We look at the importance of chromatographic purification in the production of medical-grade cannabidiol (CBD) for modern therapeutics.

7 Regulatory Considerations when Sourcing an Alternative Resin Supplier

Feb 19, 2020 /

Important regulatory considerations when sourcing a new resin supplier.

The Importance of Dynamic Binding Capacity in mAb Purification

Jan 23, 2020 /

There is now greater pressure on downstream purification processes to meet the demand from increased cell titers. But how can you meet this demand without negatively impacting your manufacturing footprint and process economy?

Industrial Adsorbents Presentation

Jan 22, 2020 /

A presentation by Fred Ghanem looking at the two new product ranges of industrial adsorbents from Purolite Life Sciences.

Replacing the 'art' of column packing with science

Nov 20, 2019 /

A state-of-the-art column packing training facility, with best-in-class pilot and process-scale equipment for optimal MAb bioprocessing.

Laboratory Scale Columns for Performance Screening

Oct 30, 2019 /

An analysis between two different agarose-based chromatography resins, packed as per manufacturer’s instructions into two commonly-used columns at smaller scales

The Praesto® Agarose Production Facility | A Year On...

Sep 27, 2019 /

Celebrating the 1 year anniversary of one of the world's largest agarose resin manufacturing sites

Why Agarose?

Jul 31, 2019 /

For the purposes of chromatography, agarose is widely considered the best material available for the protein purification resins.

Explaining Volume and Number Particle Size Distribution in Resins

Jul 10, 2019 /

An explanation of volume and number particle size distribution in chromatography resins.

Expanding the Frontiers of Biocatalysis

Jun 17, 2019 /

Discover how to optimise processes using modern, robust, high performing enzyme carriers

Purolite Life Sciences - providing regulatory support in life sciences

Jun 13, 2019 /

The regulatory environment is ever-changing, driven by increasing regulatory requirements, increasing development costs and times, and market pressures impacting pharmaceutical and food industries.

R&D Update - Q3 - 2019 - Praesto XS

Jun 4, 2019 /

Join us for round-up of key R&D updates each quarter.

Packing for Efficiency

May 24, 2019 /

In order that the purification process and the final product are robust and secure, it is vital that chromotography columns are properly packed and qualified in a reasonable time frame.

The Future in Protein A Affinity Matrix Design | Part Three

May 8, 2019 /

Praesto® Jetted A50 resin is the first product designed by combining the new technology for continuous manufacturing of agarose beads with a novel alkaline-stable Protein A ligand.

The Future in Protein A Affinity Matrix Design | Part Two

Apr 29, 2019 /

With the continued growth and therapeutic commercial importance of mAb production, the availability of high-quality agarose resins is critical.

The Future in Protein A Affinity Matrix Design | Part One

Apr 23, 2019 /

Protein A affinity chromatography continues to be the preferred method for commercial purification of antibodies because of its high selectivity and robust resin performance over repeated purification cycles.

Case Study CalB immo Plus Immobilized Enzyme

Apr 16, 2019 /

In addition to a complete range of enzyme carriers - Lifetech™ ECR, the Purolite Life Sciences team has developed ready-to-use immobilized enzymes for a variety of applications in industry. The immobilized enzymes developed at Purolite cover different groups such as transferases, hydrolases, isomerases etc.

What is Jetting?

Feb 22, 2019 /

What can our jetting process do for you? Purolite Life Sciences uses Jetting to produce both copolymer and agarose-based resins, and are the only resin supplier in the world with the ability to manufacture jetted agarose products.

Discover the Chromalite® resins range

Oct 26, 2018 /

Purolite has developed the widest range of synthetic polymers for all of your purification and chromatography needs. For any separation by reverse-phase (RP) or ion exchange (IEX); our Chromalite® range has a product for your needs.

Purolite Corporation implements Ideagen’s software

Sep 11, 2018 /

Purolite Life Sciences has adopted software from Ideagen as it looks to enhance quality and compliance processes at its new manufacturing, research, development and quality centre of excellence site based in South Wales.

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