Oligonucleotide Purification Resins

Oligonucleotide synthesis results in the formation of impurities, making efficient chromatographic purification a key processing step to obtain the purity required for pharmaceutical use. Our chromatographic resins are designed for optimal separation and purification performance at HPLC to manufacturing scales. Purolite-patented technology for monodisperse resin beads enables you to achieve your target purity and yields.

We have a range of chemistries functionalized onto Agarose, Styrene/DVB or Methacrylic polymers to suit your process requirements. 

Our resins are ideal for:

  • Adsorption
  • Reverse phase chromatography
  • HPLC (bulk or pre-packed)
  • Solid phase extraction
  • Ion exchange chromatography

Oligonucleotide Purification Products by Application


Solid Phase Extraction