Chromatography and Vital Medicines

Chromatography resins offer a powerful, scalable tool for efficient purification of vital medicines such as antibiotics and monoclonal antibodies, an important therapeutic used in the treatment of cancers, arthritis, diabetes and other generally age-related ailments. Chromatography resins achieve the maximum purity possible for these vital products.

We offer a range of resins covering Affinity, Ion Exchange, HPLC, Reverse-Phase, Solid Phase Extraction and Adsorption applications for purification of antibodies, proteins, peptides, oligonucleotides and other biomolecules. These are available on agarose, methacrylic and polydivinylbenzene base matrices.

Biocatalysis and Vital Medicines

Biocatalysis using immobilized enzymes offers distinct advantages over chemical methods, such as selectivity, safety, performance and sustainability in industrial processes. As such immobilized enzymes are increasingly being implemented into pharmaceutical production processes.

Our LifetechTM range of enzyme immobilization products have numerous applications in the production of vital medicines, including antibiotics and treatments for ailments such as osteoporosis, hepatitis and diabetes. Immobilized enzymes also have a significant presence in various medical devices.

Literature

Security of Supply

Ensuring reliable availability of resins is vital to customers and is of paramount importance to Purolite. As a leading supplier of resin media to the world’s most regulated industries, we recognise that Purolite’s resins are critical purification products. As such Purolite has a real-world security-of-supply system in place to support your process requirements for business continuity. 

Regulatory Support

Purolite is a global leader in resin technology, and one of the world’s largest developers and manufacturers of high-quality chromatographic resins, enzyme carriers, ion exchange resins, APIs, adsorbents and specialty resins.

All Purolite Life Sciences products are of premium quality and are produced in our ISO-certified production facilities in the UK, Romania, China and the USA.

For over 35 years, Purolite has supplied specialty resin technology to industries within complex regulatory environments including biotechnology, pharmaceutical, food, fine chemical and electric power generation.

Purolite complies with required national and international regulations, as well as many voluntary specialty certifications. These include: • Part II of the EU GMP Guide • US FDA Current Good Manufacturing Practice (CGMP) regulations • US FDA CFR - Code of Federal Regulations including Title 21 • GMO/TSE/BSE free • ResAP(2004)3 • NSF/ANSI 61/WRAS standards • REACH regulations • ISO 9001:2015 quality system specifications, • ISO 14001:2015 Environmental Management System requirements • OHSAS18001:2007 • RoHS Directive 2011/65/EU • Halal and Kosher requirements

We also hold Drug Master Files with the US FDA, Japan, Canada and EU.

Medicines Products by Application

Biomolecule Separation