Core Technologies

As the global leader in resin technology, we develop and manufacture small beads that are used in the most regulated industries in the world to separate, remove or recover very specific elements and compounds.

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Product Types
Product Types
Adsorbents
Adsorbents
Overview Adsorbents for Enzyme Immobilization Adsorbents for Gases and Organic Vapors Adsorbents of Organic Pollutants Citrus Juice Debittering Corn Sweetener Refining Inorganic Salt Separation Using Adsorbents Patulin Removal Polyphenol Recovery
Catalyst Chelation Resins Chromatographic Separation Resins Fine Mesh Resins Inert Spacer Resins Mixed Bed Resins
Mixed Bed Resins
Overview Mixed Bed Nuclear Mixed Bed Ultrapure Water
Strong Acid Cation Resin Strong Base Anion Resin Weak Acid Cation Resin
Weak Acid Cation Resin
Overview Weak Acid Cation Macroporous Weak Acid Cation Porous
Weak Base Anion Resin
Weak Base Anion Resin
Overview Weak Base Anion Gel Weak Base Anion Macroporous
Industries
Industries
Chemical Processing and Petrochemical Fine Chemicals
Fine Chemicals
Overview Cosmetics Fragrances
Food and Beverage
Food and Beverage
Overview Dairy Flavors Food Ingredients Fruit Juice
Fruit Juice
Overview Citrus Juice Debittering Patulin Removal Polyphenolic Compound Recovery
Gelatin and Collagen Organic Acid Purification Sugar
Sugar
Overview Beet Sugar Refining Cane Sugar Refining
Sweetener
Sweetener
Overview Corn Sweetener Refining
Additional Food and Beverage
Hydrometallurgy Metals Plating Oil & Gas Potable and Groundwater
Potable and Groundwater
Overview Arsenic Nitrate PFAS TOC, Bromide and DBP
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Power
Overview Fossil Nuclear
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Overview Nuclear Applications for Ion Exchange Resin
Pulp & Paper Semiconductor - Electronics
Applications
Applications
Adsorption Catalysis Condensate Polishing Demineralization Metal Removal and Recovery Organics Removal Softening

Healthcare & Life Sciences

With 40 years of manufacturing expertise and 30 years of regulatory experience, we supply leading separation, purification and extraction technologies to support chromatography and biocatalysis applications in healthcare and life sciences.

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Biopharmaceuticals and Antibody Processing
Biopharmaceuticals and Antibody Processing
Overview Antibody Purification Protein Purification
Pharmaceutical
Pharmaceutical
Overview APIs / Excipients Biocatalysis Milling Media Oligonucleotide Purification Peptide Purification Plasma Fractionation Radionuclide Separation
Medical Devices & Diagnostics
Medical Devices & Diagnostics
Overview Biofluid Treatment Diagnostics Enteral Nutrition
Nutraceuticals
Nutraceuticals
Overview Amino Acid Production Cannabinoid Purification Dairy Protein Isolation
Dairy Protein Isolation
Overview Lactoferrin Extraction
Protein Purification Supplement Ingredients Vitamin Purification
Analytical Lab Testing and Screening
Analytical Lab Testing and Screening
Overview Affinity Chromatography HIS-TAG Biocatalysis Screening Ligand Addition Monoclonal Antibody Purification Kits Protein Ion Exchange Chromatography Reference / Calibration Reversed Phase Chromatography

Purolite Corporation

We are the world leader in resin-based separation, purification and extraction technology, that provides sustainable solutions for our environment, businesses and healthcare.

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About
About
About Us
About Us
Overview Leadership
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Overview Steve Brodie Don Brodie Jacob Brodie Howard Brodie
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Chromalite™ LifeTech™ Macronet™ Microlite® Praesto® Purophase™ Purofine® Puromet™ Puromill™ Puropack® Purosorb™ Shallow Shell™ UltraClean™
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Purolite Resin System Modeling (PRSM™) Unit Conversion Calculator
Peptide Purification / Pharmaceutical / Healthcare & Life Sciences / purolite

Peptide Purification

Chromatographic resins for optimized resolution in peptide purification

Applications

Bivalirudin Purification

Here to Help

Our always-ready technical support and service teams go the extra step to be your most trusted resource. We're here for you.

Overview
Literature

Peptide Purification Resins

Peptides are regularly used for various industrial applications such as drug, cosmetic and food manufacture. The separation of peptides can be a time-consuming stage in the determination of the amino acid sequence of a protein during the purification process. But with our range of chromatographic resins, we offer enhanced results in yield, purity and throughput to make your processes more efficient and cost-effective.

We have a range of chemistries functionalized onto Agarose, Styrene/DVB or Methacrylic polymers to suit your process requirements.

Our resins are ideal for:

  • Adsorption

  • Reversed-phase chromatography

  • HPLC (bulk or pre-packed)

  • Solid phase extraction

  • Ion exchange chromatography

Combining Solid Phase Synthesis and Chromatographic Purification for Efficient Peptide Manufacture
Development of a Novel Combined IEX-RP Chromatographic Process for the Purification of Bivalirudin

Peptide Purification Products by Application

Adsorbents

PAD1200

Polydivinylbenzene Macroporous Adsorbent Non-Ionic Form, 240 Å pores

PAD400

Polydivinylbenzene Macroporous Adsorbent Non-Ionic Form, 360 Å pores

PAD500

Polydivinylbenzene Macroporous Adsorbent Non-Ionic Form, 110 Å pores

PAD610

Polymethacrylic/DVB Macroporous Adsorbent Non-Ionic Form, 300 Å pores

PAD900

Polydivinylbenzene Macroporous Adsorbent Non-Ionic Form, 220 Å pores

PAD950

Polymethacrylic Macroporous Adsorbent Non-Ionic Form, 120 Å pores

PAD950C

Polymethacrylic Macroporous Adsorbent Non-Ionic Form, 120 Å pores, Course Particle Size

Anion Exchange Chromatography - Peptides

MDEA/M

Diethylamino Methacrylate Macroporous Weak Anion Exchanger, 75 - 125 µm

MQ/C

Quaternary Ammonium Methacrylate Macroporous Strong Anion Exchanger, 100 - 300 µm

MQ/F

Quaternary Ammonium Methacrylate Macroporous Strong Anion Exchanger, 40 - 90 µm

Cation Exchange Chromatography - Peptides

MCM/C

Carboxymethyl Methacrylate Macroporous Weak Cation Exchanger, 100 - 300 µm

MCM/F

Carboxymethyl Methacrylate Macroporous Weak Cation Exchanger, 40 - 90 µm

MCM/M

Carboxymethyl Methacrylate Macroporous Weak Cation Exchanger, 75 - 125 µm

MS/F

Sulfopropyl Methacrylate Macroporous Strong Cation Exchanger, 40 - 90 µm

Pre-Packed HPLC Columns

10AD2 (HPLC Column)

Polystyrenic Macroporous Adsorbent

15AD2 (HPLC Column)

Polystyrenic Macroporous Adsorbent

5AD2 (HPLC Column)

Polystyrenic Macroporous Adsorbent

Reversed Phase Chromatography

10AD2

Polystyrenic Macroporous Adsorbent Non-functionalized resin, 10 µm

10AD2Q

Polystyrenic Macroporous adsorbent Quaternary Amine Functionalized Resin, 10 µm

10AD2S

Polystyrenic Macroporous adsorbent Sulfonate Functionalized Resin, 10 µm

15AD2

Polystyrenic Macroporous adsorbent Non-functionalized Resin, 15 µm

15AD2Q

Polystyrenic Macroporous adsorbent Quaternary Amine Functionalized Resin, 15 µm

15AD2S

Polystyrenic Macroporous adsorbent Sulfonate Functionalized Resin, 15 µm

30AD2

Polystyrenic Macroporous adsorbent Non-functionalized Resin, 30 µm

5AD2

Polystyrenic Macroporous Adsorbent

PCG1200C

Polystyrenic Macroporous Adsorbent

PCG1200M

Polystyrenic Macroporous Adsorbent

PCG900C

Polystyrenic Macroporous Adsorbent

PCG900M

Polystyrenic Macroporous Adsorbent

PCG950C

Macroporous Polymethacrylic Adsorbent

PCG950M

Macroporous Polymethacrylic Adsorbent