Accelerate your biologic drug development with Praesto®
Nos équipes de support technique et de service toujours prêtes font un pas supplémentaire pour devenir votre ressource la plus fiable. Nous sommes là pour vous.
Acrylics are one of, if not the most versatile family of monomers. They can be used to prepare polymers with properties including rigidity, flexibility, ionic and non-ionic, hydrophobic or hydrophilic.
This particular example is a monomer manufactured by BASF and has:
Traditional chemical process employs temperatures of 80-100 °C and inhibitors/acid catalysis
Lipases do not catalyze efficiently the acrylation reaction
BASF developed a mutein of CalB that catalyze acrylation at moderate T (40 °C)
BASF Patent US2010/0273223A1
Important in steroselective process of organic synthesis, so are used as disolving agents and building blocks of chiral auxiliries in many chemical reactions.
This example is manufactured by BASF:
Chemical compounds: chiral transamidation for the synthesis of (S)-phenylethylamine
BASF Patent WO 1997010201 A1
Immobilized enzymes are key for the pesticide and herbicide application due to the large quantity that goes into these products.
In the first range of herbicides targets specific plants via enzyme inhibition. Within this group, there is are a number of common active compounds containing similar chemical structures.
A current global issue with these products is the volume of chemicals currently being used on plants and crops, this process aims to reduce the volume by half.
One example of this can be seen on the right, manufactured by BASF:
Racemic Dimethenamid was developed by Sandoz, but sold to BASF in 1996
Made in Geismar BASF site (USA)
BASF implemented the single enantiomer Dimethenamid-P named Outlook®
BASF Patent DE 19837745 A1