Accelerate your biologic
drug development with
Purolite™ chromatography resins.
En tant que leader mondial de la technologie des résines, nous développons et fabriquons de petites billes qui sont utilisées dans les industries les plus réglementées au monde pour séparer, éliminer ou récupérer des éléments et composés très spécifiques.
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Avec 40 ans d'expertise en fabrication et 30 ans d'expérience en réglementation, nous fournissons des technologies de séparation, de purification et d'extraction de pointe pour soutenir les applications de chromatographie et de biocatalyse dans les soins de santé et les sciences de la vie.
(Pages Sciences de la vie actuellement en anglais uniquement)
Nous sommes le leader mondial des technologies de séparation, de purification et d'extraction à base de résine, qui fournissent des solutions durables pour notre environnement, nos entreprises et nos soins de santé.
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Capacity
Purolite Jetted A50 exhibits high dynamic binding capacities for conventional monoclonal antibodies, up to 70 g/L at a 10-minute residence time. Patented Jetting technology, coupled with the latest protein A technology, allows for high capacity at even low residence times. The resin is uniquely suited to address the demands of modern bioprocessing, from high-titre cell cultures to continuous chromatography formats.
Flow
The uniform particle size and highly cross-linked agarose base bead provides increased surface area without severely impacting pressure flow properties. Praesto Jetted A50 has excellent flow properties, with up to 200 cm/h achievable in a standard mAb platform process. This has been verified in process scale columns.
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Capacity
Purolite Jetted A50 HipH exhibits high dynamic binding capacities for conventional monoclonal antibodies, up to 60 g/L at a 6-minute residence time. Patented Jetting technology, coupled with the latest protein A technology, allows for high capacity at even low residence times. The resin is uniquely suited to address the demands of modern bioprocessing, from high-titre cell cultures to continuous chromatography formats.
Read the latest paper Evaluation of mild pH elution protein A resins for antibodies and Fc-fusion proteins and find out how Purolite Jetted A50 HipH is an ideal candidate for a platform protein A resin that provides flexibility for pH-sensitive proteins and stable mAbs, while preserving product quality, recovery, and seamless integration into a downstream process.
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