Throughput & Productivity Calculator Guiding Material

Praesto® Jetted A50
Praesto® Jetted A50
Praesto® Jetted A50 HipH

Capacity
Praesto Jetted A50 exhibits high dynamic binding capacities for conventional monoclonal antibodies, up to 70 g/L at a 10-minute residence time. Patented Jetting technology, coupled with the latest protein A technology, allows for high capacity at even low residence times. The resin is uniquely suited to address the demands of modern bioprocessing, from high-titre cell cultures to continuous chromatography formats.

Flow
The uniform particle size and highly cross-linked agarose base bead provides increased surface area without severely impacting pressure flow properties. Praesto Jetted A50 has excellent flow properties, with up to 200 cm/h achievable in a standard mAb platform process. This has been verified in process scale columns.

Capacity
Praesto Jetted A50 HipH exhibits high dynamic binding capacities for conventional monoclonal antibodies, up to 60 g/L at a 6-minute residence time. Patented Jetting technology, coupled with the latest protein A technology, allows for high capacity at even low residence times. The resin is uniquely suited to address the demands of modern bioprocessing, from high-titre cell cultures to continuous chromatography formats.
 

Flow
The uniform particle size and highly cross-linked agarose base bead provides increased surface area without severely impacting pressure flow properties. Praesto Jetted A50 HipH has excellent flow properties, with up to 200 cm/h achievable in a standard mAb platform process. This has been verified in process scale columns.

Journal of Chromatography A 

Evaluation of mild pH elution protein A resins for antibodies and Fc-fusion proteins

Read the latest journal from Science Direct and find out how Jetted A50 HipH is an ideal candidate for a platform protein A resin that provides flexibility for pH-sensitive proteins and stable mAbs, while preserving product quality, recovery, and seamless integration into a downstream process.

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