Lifetech ECR8215M is a methacrylate polymer functionalised with epoxy groups, used for covalent enzyme immobilization. Epoxy groups form very stable covalent linkages with different protein surface groups as ε-NH2 in Lys or nucleophiles  (amino, thiol, phenolic). Immobilization is performed under very mild experimental conditions of pH and temperature, at high ionic buffer strength.  Lifetech ECR8215M main features are the very high porosity, the hydrophilicity and its optimal use in batch reactors and columns.

Principal Applications

  • Covalent immobilization of enzymes
  • Epoxides form very stable covalent linkages
  • Suitable for immobilization of a wide range of enzymes (including hydrolases)
  • Coupling of specific ligands to create affinity resin

Advantages

  • High porosity
  • Easy covalent multipoint immobilization
  • Hydrophilic resin
  • Optimal for use in continuous column reactors

Systems

  • Suitable for batch and column configuration
  • Optimal for all applications in aqueous media

Regulatory Approvals

  • ResAP(2004)3 Status (food grade)
  • Halal
  • Kosher
  • TSE/BSE/GMO free

Typical Packaging

  • 50g
  • 250g
  • 1Kg

Typical Physical & Chemical Characteristics:

Appearance White to off white beads
Functional Group Epoxy
Supplied as Wet
Particle Size Range 300 - 710 µm
Pore Diameter 1200 - 1800 Å
Total moisture 70 - 80 %
pH limit stability 5 - 9
Recommended Storage 2 - 8 °C
Expiry date (from date of manufacture) 6 months