Lifetech ECR8204M is a methacrylate polymer functionalised with epoxy groups, used for covalent enzyme immobilization. Epoxides form very stable covalent linkages with different protein surface groups as ε-NH2 in Lys or nucleophiles  (amino, thiol, phenolic). Immobilization is performed under very mild experimental conditions of pH and temperature, at high ionic buffer strength. Lifetech ECR8204M main features are the low porosity, the hydrophilicity, high mechanical strengh and it is optimal for use in batch reactors and columns.

Principal Applications

  • Covalent immobilization of enzymes
  • Epoxides form very stable covalent linkages
  • Suitable for immobilization of a wide range of enzymes (including hydrolases)
  • Coupling of specific ligands to create affinity resin

Advantages

  • Low porosity
  • Easy covalent multipoint immobilization
  • Hydrophilic resin
  • High mechanical strength
  • Optimal for use in batch reactors

Systems

  • Suitable for batch and column configuration
  • Optimal for all applications in aqueous media

Regulatory Approvals

  • TSE/BSE/GMO free
  • Council of Europe Resolution ResAP (2004)3
  • Halal
  • Kosher

Typical Packaging

  • 50g
  • 250g
  • 1Kg

Typical Physical & Chemical Characteristics:

Appearance White to off white beads
Functional Group Epoxy
Supplied as Wet
Particle Size Range 300 - 710 µm
Pore Diameter 300 - 600 Å
Total moisture 55 - 70 %
pH limit stability 5 - 9
Recommended Storage 2 - 8 °C
Expiry date (from date of manufacture) 6 months