CalB immo 5872 was jointly developed and is co-marketed by c-LEcta and Purolite.
Immobilized, recombinant Lipase B from Candida antarctica (CalB) produced by microbial fermentation with Pichia pastoris. CalB immo 5872 is an adsorbed preparation and is suitable for applications in solvent-free systems like oils, as well as organic solvents and it and can be used for (regio- and stereoselective) esterifications and transesterifications. The lipase is immobilized by adsorption through interaction of hydrophobic surface of lipase with aromatic rings of Purolite’s highly hydrophobic carrier made of styrene and DVB co-polymer).
CalB Immo 5872 has many advantages compared to similar commercial preparations:
- cost-effective
- possibility to use in oils, organic solvent and bi-phasic systems
- security of supply from kg to ton scale
- full regulatory support

Principal Applications

  • Esterifications (regio- and stereo-selective)
  • Transesterfication
  • Amidation
  • Fats and oils modification
  • Hydrolysis of esters

Advantages

  • High mechanical stability
  • Cost-effective
  • Optimal for all applications in organic solvents
  • Immobilized by adsorption on hydrophobic carrier macroporous polydivinylbenzene
  • Security of supply from Kg to ton scale
  • Full regulatory support

Regulatory Approvals

  • Compliant with FDA regulation 21CFR177.2710
  • Compliant with ResAP(2004) 3
  • Halal
  • Kosher in 2018
  • TSE/BSE/GMO free

Typical Packaging

  • 10g
  • 50g
  • 250 g
  • 1Kg

Typical Physical & Chemical Characteristics:

Appearance White to slightly yellow spherical beads
Supplied as Dry
Particle Size Range 300 - 710 µm
Total moisture 0 - 5 %
Enzyme activity (min.) 3500 PLU/gdry
Expiry date (from date of manufacture) 1 year
Optimal storage condition 2 - 8 °C